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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:renal cell carcinoma
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Accession:DOID:4450 term browser browse the term
Definition:A renal carcinoma that has_material_basis_in the lining of the proximal convoluted renal tubule of the kidney. (DO)
Synonyms:exact_synonym: Grawitz tumor;   RCC;   adenocarcinoma of kidney;   chromophil renal cell carcinoma;   hypernephroid carcinoma;   hypernephroid carcinomas;   hypernephroma;   hypernephromas;   nephroid carcinoma;   nephroid carcinomas;   renal adenocarcinoma;   renal cell adenocarcinoma;   renal cell adenocarcinomas;   renal cell cancer;   renal cell cancers;   renal cell carcinomas
 narrow_synonym: ADENOCARCINOMA OF KIDNEY NONPAPILLARY RENAL CARCINOMA 1 LOCUS;   NRC1;   Unclassified Renal Cell Carcinoma;   renal cell carcinoma with paraneoplastic erythrocytosis;   renal cell carcinoma, somatic
 primary_id: MESH:D002292
 alt_id: OMIM:144700
 xref: EFO:0000681;   EFO:0005708;   EFO:1000603;   GARD:13215;   ICDO:8312/3;   NCI:C9385;   ORDO:217071
For additional species annotation, visit the Alliance of Genome Resources.

GViewer not supported for the selected species.

show annotations for term's descendants           Sort by:
renal cell carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB1 ATP binding cassette subfamily B member 1 disease_progression ISO DNA:polymorphism: :3435C>T (human) RGD PMID:12089380 PMID:17177989 RGD:2315557 RGD:2315559 NCBI chr21:61,211,044...61,430,691
Ensembl chr21:61,322,748...61,529,274 		JBrowse link
G ABCG2 ATP binding cassette subfamily G member 2 (JR blood group) susceptibility ISO DNA:polymorphism: :p.Q141K (human) RGD PMID:15906349 RGD:2315569 NCBI chr 7:36,458,110...36,599,753 JBrowse link
G ACHE acetylcholinesterase (Cartwright blood group) ISO CTD Direct Evidence: marker/mechanism CTD PMID:18482720 NCBI chr28:12,328,304...12,335,302
Ensembl chr28:12,331,039...12,335,076 		JBrowse link
G ACY1 aminoacylase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15108329 NCBI chr22:13,353,446...13,359,274
Ensembl chr22:13,353,588...13,359,569 		JBrowse link
G ADIPOQ adiponectin, C1Q and collagen domain containing ISO CTD Direct Evidence: marker/mechanism CTD PMID:29723618 NCBI chr15:81,128,427...81,142,779
Ensembl chr15:81,129,795...81,147,391 		JBrowse link
G AFP alpha fetoprotein ISO RGD PMID:1714107 RGD:2292042 NCBI chr 7:21,904,225...21,924,105
Ensembl chr 7:21,905,154...21,924,092 		JBrowse link
G AGTR1 angiotensin II receptor type 1 severity ISO protein:increased expression:kidney RGD PMID:21102591 RGD:6903280 NCBI chr15:41,957,826...42,002,776 JBrowse link
G AGTR2 angiotensin II receptor type 2 disease_progression ISO protein:increased expression:kidney RGD PMID:21102591 RGD:6903280
G AHNAK AHNAK nucleoprotein ISO CTD Direct Evidence: marker/mechanism CTD PMID:22138691 NCBI chr 1:11,352,848...11,384,944 JBrowse link
G AKAP13 A-kinase anchoring protein 13 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22138691 NCBI chr29:4,009,921...4,364,226
Ensembl chr29:4,106,732...4,359,516 		JBrowse link
G AKT1 AKT serine/threonine kinase 1 ISO protein:increased serine phosphorylation:kidney RGD PMID:17681738 RGD:1643331 NCBI chr24:82,704,087...82,730,711
Ensembl chr24:82,704,068...82,727,698 		JBrowse link
G AKT3 AKT serine/threonine kinase 3 susceptibility ISO DNA:missense mutation:exon, intron:multiple RGD PMID:23378641 RGD:13503319 NCBI chr25:80,509,701...80,878,792
Ensembl chr25:80,515,168...80,816,018 		JBrowse link
G ALAD aminolevulinate dehydratase ISO CTD Direct Evidence: marker/mechanism CTD PMID:21799727 NCBI chr12:26,173,063...26,185,456
Ensembl chr12:26,173,096...26,189,845 		JBrowse link
G ALDH1A1 aldehyde dehydrogenase 1 family member A1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15108329 NCBI chr12:83,949,529...84,092,452
Ensembl chr12:83,949,399...84,009,003 		JBrowse link
G ALK ALK receptor tyrosine kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:22743654 NCBI chr14:77,632,809...78,408,307 JBrowse link
G ALOX12 arachidonate 12-lipoxygenase, 12S type ISO protein:increased expression:kidney RGD PMID:14654968 RGD:2315610 NCBI chr16:6,355,795...6,370,051
Ensembl chr16:6,356,058...6,369,738 		JBrowse link
G ALOX12B arachidonate 12-lipoxygenase, 12R type ISO CTD Direct Evidence: marker/mechanism CTD PMID:30258081 NCBI chr16:7,454,950...7,470,949
Ensembl chr16:7,455,044...7,469,934 		JBrowse link
G ALOX5 arachidonate 5-lipoxygenase ISO CTD Direct Evidence: marker/mechanism CTD PMID:30258081 NCBI chr 9:41,085,257...41,145,760
Ensembl chr 9:41,085,361...41,145,331 		JBrowse link
G AMACR alpha-methylacyl-CoA racemase ISO RGD PMID:14707866 RGD:2315633 NCBI chr 4:33,221,777...33,244,829
Ensembl chr 4:33,225,754...33,244,836 		JBrowse link
G ANG angiogenin ISO protein:increased expression:serum RGD PMID:18808740 RGD:2325699 NCBI chr29:21,215,985...21,226,927 JBrowse link
G ANGPT1 angiopoietin 1 severity ISO mRNA:altered expression:kidney RGD PMID:17505508 RGD:1643335 NCBI chr 8:102,020,346...102,268,443 JBrowse link
G ANXA1 annexin A1 ISO RGD PMID:14587099 RGD:7421570 NCBI chr12:84,207,818...84,226,438
Ensembl chr12:84,207,820...84,226,562 		JBrowse link
G ANXA2 annexin A2 ISO RGD PMID:14587099 RGD:7421570 NCBI chr26:23,100,000...23,147,687
Ensembl chr26:23,099,992...23,145,457 		JBrowse link
G ANXA4 annexin A4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15108329 NCBI chr14:37,297,960...37,384,187
Ensembl chr14:37,297,652...37,344,884 		JBrowse link
G AP5M1 adaptor related protein complex 5 subunit mu 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23797736 NCBI chr24:34,449,826...34,472,141
Ensembl chr24:34,450,227...34,473,732 		JBrowse link
G APAF1 apoptotic peptidase activating factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17133271 NCBI chr11:93,942,137...94,024,728
Ensembl chr11:93,942,103...94,024,457 		JBrowse link
G APC APC regulator of WNT signaling pathway severity
disease_progression
onset		 ISO DNA:LOH: :
DNA,protein:LOH,decreased expression: :		 RGD PMID:10426194 PMID:15203750 PMID:16116480 RGD:7242056 RGD:7242059 RGD:7242060 NCBI chr23:15,992,437...16,135,117
Ensembl chr23:16,042,287...16,137,067 		JBrowse link
G APRT adenine phosphoribosyltransferase ISO CTD Direct Evidence: marker/mechanism CTD PMID:15108329 NCBI chr 5:74,196,858...74,199,789
Ensembl chr 5:74,194,013...74,199,891 		JBrowse link
G ARNT aryl hydrocarbon receptor nuclear translocator treatment ISO DNA:missense mutation: :pF446L (human) RGD PMID:27595394 RGD:13503335
G ASB15 ankyrin repeat and SOCS box containing 15 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22138691 NCBI chr21:92,358,898...92,436,166
Ensembl chr21:92,398,306...92,428,794 		JBrowse link
G ASZ1 ankyrin repeat, SAM and basic leucine zipper domain containing 1 ISO ClinVar Annotator: match by term: Renal adenocarcinoma | ClinVar Annotator: match by term: Renal cell carcinoma | ClinVar Annotator: match by term: Renal cell carcinoma, somatic ClinVar PMID:28492532 NCBI chr21:86,042,400...86,108,247
Ensembl chr21:86,042,691...86,107,099 		JBrowse link
G ATM ATM serine/threonine kinase ISO ClinVar Annotator: match by term: Renal adenocarcinoma ClinVar PMID:10571946 NCBI chr 1:99,653,208...99,786,889
Ensembl chr 1:99,653,139...99,791,520 		JBrowse link
G ATP5MC2 ATP synthase membrane subunit c locus 2 ISO DNA:hypermethylation:promoter RGD PMID:21132003 RGD:14696812 NCBI chr11:49,768,977...49,780,664
Ensembl chr11:49,768,783...49,780,081 		JBrowse link
G AURKA aurora kinase A ISO mRNA, protein:increased expression:kidney RGD PMID:17349527 RGD:1643346 NCBI chr 2:7,730,060...7,753,167
Ensembl chr 2:7,734,128...7,752,395 		JBrowse link
G BAD BCL2 associated agonist of cell death ISO RGD PMID:15851405 RGD:2292677 NCBI chr 1:9,949,717...9,964,433
Ensembl chr 1:9,949,762...9,964,432 		JBrowse link
G BAK1 BCL2 antagonist/killer 1 severity ISO RGD PMID:9894249 RGD:2315703 NCBI chr17:38,492,776...38,502,534
Ensembl chr17:38,492,858...38,501,281 		JBrowse link
G BAP1 BRCA1 associated protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22138691 PMID:22683710 PMID:23797736 PMID:25231345 NCBI chr22:13,765,510...13,774,866
Ensembl chr22:13,764,686...13,774,740 		JBrowse link
G BCHE butyrylcholinesterase ISO CTD Direct Evidence: marker/mechanism CTD PMID:18482720 NCBI chr15:23,708,121...23,778,027
Ensembl chr15:23,708,155...23,778,286 		JBrowse link
G BCL2 BCL2 apoptosis regulator disease_progression ISO RGD PMID:17482919 PMID:18283311 RGD:2293019 RGD:2298896 NCBI chr18:16,440,560...16,643,187
Ensembl chr18:16,441,733...16,637,895 		JBrowse link
G BCL2L1 BCL2 like 1 ISO RGD PMID:12025227 RGD:1643483 NCBI chr 2:36,059,024...36,118,332
Ensembl chr 2:36,058,919...36,116,470 		JBrowse link
G BIK BCL2 interacting killer ISO protein:decreased expression:kidney RGD PMID:16322756 RGD:14394818 NCBI chr19:25,632,837...25,658,951
Ensembl chr19:25,652,945...25,658,541 		JBrowse link
G BIRC2 baculoviral IAP repeat containing 2 disease_progression ISO mRNA:altered expression:kidney RGD PMID:17154176 RGD:1643526 NCBI chr 1:93,721,449...93,746,638 JBrowse link
G BIRC3 baculoviral IAP repeat containing 3 ISO mRNA:altered expression:kidney RGD PMID:17154176 RGD:1643526 NCBI chr 1:93,692,239...93,711,905 JBrowse link
G BIRC5 baculoviral IAP repeat containing 5 disease_progression ISO CTD Direct Evidence: therapeutic
mRNA:splice variant
protein:increased expression:kidney		 CTD
RGD		 PMID:12115583 PMID:16188142 PMID:17363528 RGD:2293102 RGD:2293108 NCBI chr16:70,226,824...70,237,000 JBrowse link
G BIRC7 baculoviral IAP repeat containing 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17437058 PMID:25401301 NCBI chr 2:965,811...970,983 JBrowse link
G BMP4 bone morphogenetic protein 4 severity ISO RGD PMID:17644140 RGD:1643589 NCBI chr24:31,097,673...31,104,774
Ensembl chr24:31,097,538...31,101,225 		JBrowse link
G BMP6 bone morphogenetic protein 6 ISO mRNA,protein:increased expression:kidney RGD PMID:20016212 RGD:7242419 NCBI chr17:64,279,243...64,436,356
Ensembl chr17:64,280,609...64,435,382 		JBrowse link
G BMP7 bone morphogenetic protein 7 disease_progression ISO RGD PMID:17644140 RGD:1643589 NCBI chr 2:6,856,396...6,954,948
Ensembl chr 2:6,856,453...6,954,944 		JBrowse link
G BSG basigin (Ok blood group) disease_progression ISO protein:increased expression:kidney
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:17021824 PMID:36574092 RGD:2289052 NCBI chr 6:309,579...320,209
Ensembl chr 6:309,506...321,785 		JBrowse link
G BTG2 BTG anti-proliferation factor 2 ISO mRNA:decreased expression:kidney RGD PMID:14996721 RGD:2289069 NCBI chr25:26,032,404...26,036,500
Ensembl chr25:26,034,632...26,036,538 		JBrowse link
G BTG3 BTG anti-proliferation factor 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19221000 NCBI chr 2:74,986,522...75,005,834
Ensembl chr 2:74,990,327...75,006,412 		JBrowse link
G CA9 carbonic anhydrase 9 disease_progression ISO DNA, mRNA:hypomethylation, increased expression:promoter, kidney
protein:increased expression:serum, urine		 RGD PMID:11506497 PMID:12883698 PMID:12966427 PMID:18464292 RGD:2293191 RGD:2293198 RGD:2293199 RGD:2293201 NCBI chr12:44,921,530...44,929,504
Ensembl chr12:44,921,665...44,928,831 		JBrowse link
G CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase ISO RGD PMID:7053379 RGD:10755426 NCBI chr14:80,371,154...80,399,193
Ensembl chr14:80,371,096...80,398,914 		JBrowse link
G CAPZA2 capping actin protein of muscle Z-line subunit alpha 2 ISO ClinVar Annotator: match by term: Renal adenocarcinoma | ClinVar Annotator: match by term: Renal cell carcinoma | ClinVar Annotator: match by term: Renal cell carcinoma, somatic ClinVar PMID:28492532 NCBI chr21:85,543,297...85,598,346
Ensembl chr21:85,543,271...85,601,370 		JBrowse link
G CARD11 caspase recruitment domain family member 11 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22138691
G CASP2 caspase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20208132 NCBI chr21:112,172,614...112,189,574
Ensembl chr21:112,172,733...112,188,744 		JBrowse link
G CASP3 caspase 3 ISO RGD PMID:17513560 RGD:2293308 NCBI chr 7:130,589,592...130,610,845
Ensembl chr 7:130,591,166...130,610,899 		JBrowse link
G CAV1 caveolin 1 disease_progression ISO protein:increased expression:kidney
ClinVar Annotator: match by term: Renal cell carcinoma		 RGD
ClinVar		 PMID:15247769 PMID:28492532 RGD:2289107 NCBI chr21:85,222,724...85,258,562
Ensembl chr21:85,222,879...85,258,627 		JBrowse link
G CCNB1 cyclin B1 disease_progression ISO protein:increased expression:kidney RGD PMID:16557593 RGD:2315941 NCBI chr 4:65,265,798...65,276,465
Ensembl chr 4:65,265,844...65,277,085 		JBrowse link
G CCND1 cyclin D1 ISO DNA:polymorphism RGD PMID:15538282 PMID:17924468 RGD:2289127 RGD:2289130 NCBI chr 1:4,909,616...4,922,272
Ensembl chr 1:4,907,353...4,922,357 		JBrowse link
G CCND3 cyclin D3 disease_progression ISO RGD PMID:18679818 RGD:2316007 NCBI chr17:30,107,236...30,228,449
Ensembl chr17:30,221,598...30,227,452 		JBrowse link
G CCNE1 cyclin E1 ISO mRNA, protein:increased expression:kidney RGD PMID:17726548 RGD:2289228 NCBI chr 6:24,879,923...24,888,985 JBrowse link
G CD40 CD40 molecule treatment ISO RGD PMID:12594303 PMID:15282531 PMID:20426873 RGD:11522744 RGD:7248440 RGD:7248724 NCBI chr 2:17,753,713...17,765,134
Ensembl chr 2:17,753,394...17,764,566 		JBrowse link
G CD44 CD44 molecule (IN blood group) disease_progression
severity		 ISO protein:increased expression:kidney RGD PMID:12833185 PMID:17284111 RGD:2289351 RGD:2289360 NCBI chr 1:30,039,854...30,132,646
Ensembl chr 1:30,039,749...30,132,416 		JBrowse link
G CD46 CD46 molecule ISO protein:decreased expression:tumor:expression associated with presence of complement C3d on tumor cells (p<0.02) and with tumor stage (p<0.04) RGD PMID:10744069 RGD:2293550 NCBI chr25:21,650,825...21,693,898
Ensembl chr25:21,655,969...21,693,878 		JBrowse link
G CDC14B cell division cycle 14B severity ISO mRNA:decreased expression:kidney: RGD PMID:24619757 RGD:10059341 NCBI chr12:106,520,152...106,645,468
Ensembl chr12:106,572,015...106,633,316 		JBrowse link
G CDK2 cyclin dependent kinase 2 ISO RGD PMID:16740772 RGD:2293561 NCBI chr11:51,905,085...51,910,209
Ensembl chr11:51,905,115...51,909,907 		JBrowse link
G CDK4 cyclin dependent kinase 4 ISO protein:increased expression:kidney RGD PMID:15991006 RGD:2293579 NCBI chr11:53,661,877...53,665,688
Ensembl chr11:53,659,336...53,664,861 		JBrowse link
G CDKN1B cyclin dependent kinase inhibitor 1B disease_progression ISO protein:decreased expression:kidney
mRNA, protein:increased expression:kidney		 RGD PMID:17924468 PMID:18425369 PMID:18495610 RGD:2289127 RGD:2293589 RGD:2293590 NCBI chr11:12,612,064...12,617,228
Ensembl chr11:12,612,079...12,617,531 		JBrowse link
G CFTR CF transmembrane conductance regulator ISO ClinVar Annotator: match by term: Renal adenocarcinoma | ClinVar Annotator: match by term: Renal cell carcinoma | ClinVar Annotator: match by term: Renal cell carcinoma, somatic ClinVar PMID:28492532 NCBI chr21:86,154,313...86,332,436 JBrowse link
G CNN2 calponin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15108329
G COMT catechol-O-methyltransferase susceptibility ISO DNA:polymorphism:exon RGD PMID:17220335 RGD:2289716 NCBI chr19:5,775,829...5,803,260
Ensembl chr19:5,773,225...5,785,422 		JBrowse link
G CPQ carboxypeptidase Q ISO CTD Direct Evidence: marker/mechanism CTD PMID:25401301 NCBI chr 8:91,604,736...92,095,671
Ensembl chr 8:91,738,987...92,097,126 		JBrowse link
G CRABP1 cellular retinoic acid binding protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16254461 NCBI chr26:4,987,927...4,996,431
Ensembl chr26:4,987,882...4,996,343 		JBrowse link
G CRADD CASP2 and RIPK1 domain containing adaptor with death domain ISO CTD Direct Evidence: marker/mechanism CTD PMID:20208132 NCBI chr11:89,066,952...89,246,177 JBrowse link
G CRP C-reactive protein disease_progression ISO RGD PMID:22958305 RGD:6904212 NCBI chr20:4,232,262...4,235,826
Ensembl chr20:4,232,913...4,235,377 		JBrowse link
G CRYAB crystallin alpha B ISO CTD Direct Evidence: marker/mechanism CTD PMID:15108329 NCBI chr 1:103,258,715...103,263,274
Ensembl chr 1:103,257,347...103,261,990 		JBrowse link
G CSF1R colony stimulating factor 1 receptor treatment ISO mRNA:increased expression:kidney
mouse cell line in a mouse model		 RGD PMID:18592004 PMID:22052465 PMID:32302573 RGD:150524293 RGD:2299092 RGD:7257566 NCBI chr23:52,663,290...52,723,652
Ensembl chr23:52,664,076...52,697,304 		JBrowse link
G CSMD3 CUB and Sushi multiple domains 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22138691 PMID:23797736 NCBI chr 8:106,913,123...108,143,655
Ensembl chr 8:106,914,976...107,393,443 		JBrowse link
G CTLA4 cytotoxic T-lymphocyte associated protein 4 ISO DNA:SNPs:exons:rs3087243, rs231775 (human) RGD PMID:17678726 RGD:7204723 NCBI chr10:89,637,176...89,644,436
Ensembl chr10:89,638,314...89,642,344 		JBrowse link
G CTNNA1 catenin alpha 1 disease_progression ISO protein:decreased expression:kidney RGD PMID:9355975 RGD:2289799 NCBI chr23:41,423,504...41,599,458
Ensembl chr23:41,447,675...41,600,190 		JBrowse link
G CTNNB1 catenin beta 1 disease_progression ISO ClinVar Annotator: match by term: Renal adenocarcinoma
protein:increased expression:kidney		 RGD
ClinVar		 PMID:11831984 PMID:15330191 PMID:26822237 RGD:2289794 RGD:2289835 NCBI chr22:2,679,488...2,725,034
Ensembl chr22:2,684,022...2,723,949 		JBrowse link
G CTSB cathepsin B ISO CTD Direct Evidence: marker/mechanism CTD PMID:15108329 NCBI chr 8:7,246,076...7,269,655
Ensembl chr 8:7,246,013...7,268,854 		JBrowse link
G CTSD cathepsin D ISO CTD Direct Evidence: marker/mechanism CTD PMID:15108329 NCBI chr 1:1,570,163...1,581,857
Ensembl chr 1:1,570,069...1,581,833 		JBrowse link
G CUL7 cullin 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22138691 NCBI chr17:29,106,413...29,124,408
Ensembl chr17:29,105,004...29,123,565 		JBrowse link
G CUNH11orf65 chromosome unknown C11orf65 homolog ISO ClinVar Annotator: match by term: Renal adenocarcinoma ClinVar PMID:10571946 NCBI chr 1:99,804,191...99,879,834
Ensembl chr 1:99,804,218...99,827,182 		JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 no_association ISO DNA:polymorphism: :p.I462V (human)
DNA:SNPs: :6235T>C, 4889A>G, 4887C>A (human)		 RGD PMID:9631944 PMID:11115552 PMID:22000673 PMID:22296350 RGD:7257729 RGD:7296937 RGD:7296938 RGD:7296939 NCBI chr26:8,753,236...8,759,378
Ensembl chr26:8,753,327...8,759,384 		JBrowse link
G DAPK1 death associated protein kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17133271 NCBI chr12:98,118,948...98,330,435
Ensembl chr12:98,118,603...98,330,471 		JBrowse link
G DLL4 delta like canonical Notch ligand 4 treatment ISO RGD PMID:25618828 RGD:155663382 NCBI chr26:42,056,473...42,066,283
Ensembl chr26:42,056,331...42,065,828 		JBrowse link
G DNHD1 dynein heavy chain domain 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23797736 NCBI chr 1:58,254,559...58,330,856
Ensembl chr 1:58,254,609...58,329,357 		JBrowse link
G EBAG9 estrogen receptor binding site associated antigen 9 disease_progression ISO RGD PMID:15867365 RGD:2289852 NCBI chr 8:104,240,197...104,266,768
Ensembl chr 8:104,251,418...104,264,703 		JBrowse link
G EEF2 eukaryotic translation elongation factor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15108329 NCBI chr 6:3,733,056...3,742,526
Ensembl chr 6:3,732,425...3,742,826 		JBrowse link
G EGFR epidermal growth factor receptor ISO protein:increased expression:tumor RGD PMID:18467719 RGD:2293730 NCBI chr21:3,664,622...3,853,492
Ensembl chr21:3,666,339...3,853,239 		JBrowse link
G EGLN1 egl-9 family hypoxia inducible factor 1 ISO protein:increased expression:kidney RGD PMID:20978146 RGD:13504705 NCBI chr25:68,624,754...68,685,961
Ensembl chr25:68,625,260...68,682,804 		JBrowse link
G EGLN2 egl-9 family hypoxia inducible factor 2 ISO protein:increased expression:kidney RGD PMID:20978146 RGD:13504705 NCBI chr 6:35,251,247...35,263,717
Ensembl chr 6:35,251,237...35,260,040 		JBrowse link
G ELOC elongin C ISO ClinVar Annotator: match by term: Renal adenocarcinoma ClinVar PMID:26619011 NCBI chr 8:69,546,943...69,572,694
Ensembl chr 8:69,545,965...69,560,268 		JBrowse link
G EPAS1 endothelial PAS domain protein 1 ISO CTD Direct Evidence: marker/mechanism RGD
CTD		 PMID:12750296 PMID:21131975 RGD:10395373 NCBI chr14:60,823,110...60,912,804
Ensembl chr14:60,822,815...60,912,785 		JBrowse link
G ERBB2 erb-b2 receptor tyrosine kinase 2 ISO mRNA:decreased expression:kidney
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:10897039 PMID:15360049 PMID:17296437 RGD:2289930 RGD:2289987 NCBI chr16:66,435,488...66,464,993
Ensembl chr16:66,434,251...66,464,952 		JBrowse link
G ERBB4 erb-b2 receptor tyrosine kinase 4 ISO mRNA, protein:decreased expression:kidney RGD PMID:15360049 RGD:2289987 NCBI chr10:97,099,090...98,281,697 JBrowse link
G FAAH2 fatty acid amide hydrolase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25401301 NCBI chr  X:52,970,855...53,174,812
Ensembl chr  X:52,970,693...53,175,088 		JBrowse link
G FASLG Fas ligand ISO RGD PMID:11435457 PMID:17641033 RGD:2290051 RGD:2290132 NCBI chr25:56,488,572...56,496,469
Ensembl chr25:56,489,417...56,496,251 		JBrowse link
G FGF2 fibroblast growth factor 2 disease_progression ISO protein:increased expression:serum RGD PMID:1718278 RGD:2290303 NCBI chr 7:70,089,394...70,157,423 JBrowse link
G FGFR1 fibroblast growth factor receptor 1 disease_progression ISO RGD PMID:25900027 RGD:11352663 NCBI chr 8:36,426,116...36,485,683
Ensembl chr 8:36,427,110...36,485,508 		JBrowse link
G FHIT fragile histidine triad diadenosine triphosphatase ISO DNA:translocation::t(3;8)(p14;q24.1) results in disruption of FHIT and TRC8/RNF139 genes
protein:decreased expression::reduced or negative expression in 78% of clear cell RCCs		 RGD PMID:10530564 PMID:17539022 RGD:2289870 RGD:2289903 NCBI chr22:21,006,010...22,474,056 JBrowse link
G FLCN folliculin treatment ISO OMIM
RGD		 PMID:16369488 RGD:13605606 NCBI chr16:16,245,840...16,271,465
Ensembl chr16:16,245,715...16,267,698 		JBrowse link
G FLT1 fms related receptor tyrosine kinase 1 ISO CTD Direct Evidence: therapeutic
protein:increased expression:kidney, blood, myeloid cell
mRNA:increased expression:tumor:expression significantly higher in tumors than corresponding normal tissue (p=0.01), significantly correlated with VEGF expression		 CTD
RGD		 PMID:11846206 PMID:16596207 PMID:18566400 RGD:2289960 RGD:2301250 NCBI chr 3:7,412,506...7,608,122
Ensembl chr 3:7,412,172...7,607,967 		JBrowse link
G FMN2 formin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22138691 NCBI chr25:77,187,572...77,585,773 JBrowse link
G FN1 fibronectin 1 severity ISO RGD PMID:20860816 RGD:7205637 NCBI chr10:101,177,867...101,254,613
Ensembl chr10:101,176,789...101,254,633 		JBrowse link
G FRS2 fibroblast growth factor receptor substrate 2 disease_progression ISO RGD PMID:25900027 RGD:11352663 NCBI chr11:65,097,789...65,208,373
Ensembl chr11:65,197,385...65,208,379 		JBrowse link
G FTO FTO alpha-ketoglutarate dependent dioxygenase treatment ISO RGD PMID:30648791 RGD:329812005 NCBI chr 5:39,487,304...39,900,238
Ensembl chr 5:39,487,418...39,725,747 		JBrowse link
G GHRH growth hormone releasing hormone ISO RGD PMID:10962030 RGD:2301426 NCBI chr 2:26,482,734...26,493,761
Ensembl chr 2:26,487,973...26,493,499 		JBrowse link
G GJB1 gap junction protein beta 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18264126 NCBI chr  X:61,013,991...61,019,222
Ensembl chr  X:61,017,716...61,018,567 		JBrowse link
G GRB7 growth factor receptor bound protein 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23797736 NCBI chr16:66,416,978...66,427,035
Ensembl chr16:66,416,904...66,426,300 		JBrowse link
G GSR glutathione-disulfide reductase ISO protein:decreased expression:kidney: RGD PMID:18312938 RGD:7257550 NCBI chr 8:28,778,713...28,851,907 JBrowse link
G GSTP1 glutathione S-transferase pi 1 ISO protein:increased expression:kidney
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:15108329 PMID:20464042 RGD:8547946 NCBI chr 1:6,676,897...6,679,936 JBrowse link
G HARS1 histidyl-tRNA synthetase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15108329 NCBI chr23:43,307,573...43,324,140
Ensembl chr23:43,307,415...43,323,767 		JBrowse link
G HAVCR1 hepatitis A virus cellular receptor 1 disease_progression ISO RGD PMID:23352434 RGD:7245470 NCBI chr23:59,422,769...59,454,183
Ensembl chr23:59,423,334...59,453,531 		JBrowse link
G HAVCR2 hepatitis A virus cellular receptor 2 susceptibility ISO DNA:polymorphisms: :-574G>T, +4259T>G (human) RGD PMID:22472081 RGD:7245505 NCBI chr23:59,479,794...59,501,532
Ensembl chr23:59,475,826...59,500,836 		JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha disease_progression ISO RGD PMID:19302703 RGD:2306222 NCBI chr24:38,873,830...38,927,657
Ensembl chr24:38,873,861...38,928,288 		JBrowse link
G HNF1A HNF1 homeobox A ISO OMIM NCBI chr11:116,334,935...116,358,582
Ensembl chr11:116,335,675...116,357,751 		JBrowse link
G HNF1B HNF1 homeobox B ISO OMIM NCBI chr16:30,033,486...30,097,106
Ensembl chr16:30,036,766...30,097,088 		JBrowse link
G HOXB13 homeobox B13 disease_progression ISO DNA:hypermethylation RGD PMID:16278676 RGD:2314729 NCBI chr16:69,137,561...69,141,615
Ensembl chr16:69,137,585...69,139,382 		JBrowse link
G HSPA9 heat shock protein family A (Hsp70) member 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15108329 NCBI chr23:41,230,675...41,251,177
Ensembl chr23:41,231,364...41,251,150 		JBrowse link
G HSPB1 heat shock protein family B (small) member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15108329 NCBI chr28:10,442,530...10,443,804
Ensembl chr28:10,442,398...10,443,855 		JBrowse link
G HSPD1 heat shock protein family D (Hsp60) member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15108329 NCBI chr10:83,003,266...83,017,397
Ensembl chr10:83,003,717...83,017,363 		JBrowse link
G IFNA2 interferon alpha 2 ISO CTD Direct Evidence: therapeutic CTD PMID:8886046 NCBI chr12:58,468,018...58,469,825 JBrowse link
G IGF1R insulin like growth factor 1 receptor ISO RGD PMID:17952403 RGD:7242846 NCBI chr29:17,212,206...17,534,036
Ensembl chr29:17,459,404...17,526,930 		JBrowse link
G IGFBP3 insulin like growth factor binding protein 3 ISO mRNA,protein:increased expression:tumor:27/43 (63%) by cDNA microarray, 43/58 (74%) by immunohistochemistry RGD PMID:18076934 RGD:2290003 NCBI chr21:12,905,309...12,914,199
Ensembl chr21:12,905,280...12,914,205 		JBrowse link
G IGFBP7 insulin like growth factor binding protein 7 ISO mRNA:decreased expression:kidney RGD PMID:10854235 RGD:1626565 NCBI chr 7:11,617,096...11,694,530 JBrowse link
G IL13 interleukin 13 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22317767 NCBI chr23:35,475,762...35,479,419
Ensembl chr23:35,476,490...35,478,869 		JBrowse link
G IL1RN interleukin 1 receptor antagonist ISO RGD PMID:17031403 RGD:6907413 NCBI chr14:16,136,667...16,152,451
Ensembl chr14:16,146,333...16,151,326 		JBrowse link
G IL2 interleukin 2 ISO RGD PMID:21812652 RGD:5147871 NCBI chr 7:69,729,635...69,736,279
Ensembl chr 7:69,730,282...69,734,969 		JBrowse link
G IL4R interleukin 4 receptor susceptibility
disease_progression		 ISO DNA:polymorphism:cds:p.I50V (human)
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:12171893 PMID:22317767 PMID:30472377 RGD:7207066 RGD:7207070 NCBI chr 5:25,019,638...25,069,732
Ensembl chr 5:25,046,701...25,070,015 		JBrowse link
G IL6 interleukin 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:7834629 NCBI chr21:35,577,513...35,582,385
Ensembl chr21:35,577,939...35,582,237 		JBrowse link
G IL6R interleukin 6 receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:7834629 NCBI chr20:9,345,723...9,418,963
Ensembl chr20:9,361,152...9,396,610 		JBrowse link
G INPP4B inositol polyphosphate-4-phosphatase type II B ISO CTD Direct Evidence: marker/mechanism CTD PMID:29415082 NCBI chr 7:88,929,249...89,732,375
Ensembl chr 7:88,979,493...89,461,475 		JBrowse link
G INSR insulin receptor ISO mRNA:increased expression:tumor:isoform A RGD PMID:15753986 RGD:2290462 NCBI chr 6:6,625,951...6,803,610
Ensembl chr 6:6,630,777...6,803,592 		JBrowse link
G JUN Jun proto-oncogene, AP-1 transcription factor subunit ISO protein:increased activation:tumor:associated with early carcinogenesis--10/18 (55.5%) of pT1a cases vs 11/44 (25%) of pT1b or greater cases RGD PMID:16006965 RGD:1549443 NCBI chr20:74,204,481...74,207,835
Ensembl chr20:74,205,542...74,206,546 		JBrowse link
G JUP junction plakoglobin ISO protein:decreased expression:tumor:relative to normal kidney (p<0.001), higher expression associated with better survival rate (p<0.05)
DNA:increased methylation:promoter:significantly increased methylation vs normal kidney (p < 0.01)		 RGD PMID:9891472 PMID:15701841 RGD:2291866 RGD:2291890 NCBI chr16:64,470,974...64,503,085
Ensembl chr16:64,470,959...64,503,322 		JBrowse link
G KANK1 KN motif and ankyrin repeat domains 1 ISO DNA, mRNA, protein:hypermethylation, decreased expression:kidney RGD PMID:12133830 RGD:2315654 NCBI chr12:78,775,214...79,015,538
Ensembl chr12:78,774,788...78,973,851 		JBrowse link
G KCNH1 potassium voltage-gated channel subfamily H member 1 ISO protein:increased expression:kidney (human) RGD PMID:18777199 RGD:9693695 NCBI chr25:18,353,356...18,788,472
Ensembl chr25:18,353,482...18,783,592 		JBrowse link
G KCNMA1 potassium calcium-activated channel subfamily M alpha 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23797736 NCBI chr 9:53,727,790...54,557,252
Ensembl chr 9:54,182,910...54,554,716 		JBrowse link
G KDM4C lysine demethylase 4C ISO DNA:deletion:cds (human) RGD PMID:22483639 RGD:9587741 NCBI chr12:72,346,194...72,763,040
Ensembl chr12:72,347,071...72,761,666 		JBrowse link
G KDM5C lysine demethylase 5C ISO CTD Direct Evidence: marker/mechanism CTD PMID:22138691 NCBI chr  X:49,306,472...49,356,151
Ensembl chr  X:49,321,173...49,356,100 		JBrowse link
G KDM6A lysine demethylase 6A ISO mRNA, protein:increased expression:kidney (human) RGD PMID:23057811 RGD:9587837 NCBI chr  X:42,053,272...42,291,013
Ensembl chr  X:42,053,336...42,290,526 		JBrowse link
G KDM6B lysine demethylase 6B ISO mRNA, protein:increased expression:kidney (human) RGD PMID:23057811 RGD:9587837 NCBI chr16:7,221,769...7,241,230
Ensembl chr16:7,232,426...7,241,040 		JBrowse link
G KDR kinase insert domain receptor treatment ISO RGD PMID:16763608 PMID:17332933 PMID:17653245 RGD:126925190 RGD:2301756 RGD:8552363 NCBI chr 7:13,435,059...13,482,236
Ensembl chr 7:13,435,096...13,482,771 		JBrowse link
G KEAP1 kelch like ECH associated protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23797736 NCBI chr 6:9,515,789...9,526,699
Ensembl chr 6:9,515,416...9,522,797 		JBrowse link
G KIT KIT proto-oncogene, receptor tyrosine kinase ISO chromophobe RCC only; mRNA:increased expression:tumor:positive in 6/7 chromophobe RCCs, but 0/15 clear cell RCCs and 1/15 papillary RCCs
papillary RCC only; DNA:mutation:intron:heterozygous T>A mutation in intron 17 found in 94% of cases, also protein found to be cytoplasmic not membrane-bound in 100% of cases		 RGD PMID:15073597 PMID:15780567 RGD:2292414 RGD:2292421 NCBI chr 7:13,808,104...13,891,003
Ensembl chr 7:13,808,037...13,890,976 		JBrowse link
G KLK6 kallikrein related peptidase 6 ISO protein:decreased expression:kidney RGD PMID:16340244 RGD:2314864 NCBI chr 6:43,980,680...43,991,873
Ensembl chr 6:43,980,701...43,990,060 		JBrowse link
G KRAS KRAS proto-oncogene, GTPase ISO mRNA:increased expression:kidney RGD PMID:11851621 RGD:2314914 NCBI chr11:24,963,396...25,010,747
Ensembl chr11:24,973,619...25,005,191 		JBrowse link
G KRT32 keratin 32 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23797736 NCBI chr16:64,772,775...64,781,504
Ensembl chr16:64,773,498...64,780,717 		JBrowse link
G KRT7 keratin 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15108329 PMID:16927643 NCBI chr11:48,379,460...48,394,638
Ensembl chr11:48,379,465...48,394,643 		JBrowse link
G KRT8 keratin 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15108329 NCBI chr11:49,027,879...49,051,753 JBrowse link
G L1CAM L1 cell adhesion molecule ISO CTD Direct Evidence: marker/mechanism CTD PMID:21097529 NCBI chr  X:128,285,128...128,309,173
Ensembl chr  X:128,285,130...128,299,570 		JBrowse link
G LDHB lactate dehydrogenase B ISO CTD Direct Evidence: marker/mechanism CTD PMID:15108329 NCBI chr11:21,489,815...21,511,892
Ensembl chr11:21,488,814...21,511,938 		JBrowse link
G LEP leptin resistance ISO RGD PMID:19278051 RGD:6907119 NCBI chr21:97,056,913...97,071,161
Ensembl chr21:97,057,529...97,071,220 		JBrowse link
G LMAN2L lectin, mannose binding 2 like ISO CTD Direct Evidence: marker/mechanism CTD PMID:23797736 NCBI chr14:1,039,095...1,071,178
Ensembl chr14:1,040,423...1,071,085 		JBrowse link
G LNPEP leucyl and cystinyl aminopeptidase ISO RGD PMID:17692401 RGD:2314919 NCBI chr 4:90,769,988...90,872,205
Ensembl chr 4:90,770,272...90,863,268 		JBrowse link
G LOC103217855 C-X-C chemokine receptor type 2 ISO RGD PMID:16210641 RGD:7257682 NCBI chr10:104,012,906...104,025,599
Ensembl chr10:104,022,811...104,023,893 		JBrowse link
G LOC103219957 macrophage-capping protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:15108329 NCBI chr14:21,742,163...21,761,462
Ensembl chr14:21,746,044...21,761,322 		JBrowse link
G LOC103224275 glutathione S-transferase Mu 1 susceptibility ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:14504370 PMID:18566013 PMID:26656529 RGD:2293845 NCBI chr20:23,854,969...23,861,634 JBrowse link
G LOC103233229 cadherin-1 disease_progression
onset		 ISO protein:decreased expression, altered localization:kidney, nucleus
DNA:LOH: :		 RGD PMID:15203750 PMID:17906660 RGD:2289489 RGD:7242059 NCBI chr 5:58,578,244...58,679,677
Ensembl chr 5:58,578,146...58,679,541 		JBrowse link
G LOC103237529 adhesion G protein-coupled receptor B1 severity ISO RGD PMID:21511296 RGD:13831349 NCBI chr 8:136,704,318...136,784,581
Ensembl chr 8:136,704,341...136,783,991 		JBrowse link
G LOC103242066 mucin-4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23797736 NCBI chr15:91,313,060...91,345,172 JBrowse link
G LOC103242912 nucleoside diphosphate kinase A disease_progression ISO RGD PMID:9663430 RGD:2299059 NCBI chr16:42,186,039...42,195,608
Ensembl chr16:42,185,260...42,195,616 		JBrowse link
G LRP1B LDL receptor related protein 1B ISO CTD Direct Evidence: marker/mechanism CTD PMID:22138691 NCBI chr10:25,611,400...27,511,903
Ensembl chr10:25,616,590...26,609,111 		JBrowse link
G LRRK2 leucine rich repeat kinase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22138691 NCBI chr11:36,490,775...36,634,215
Ensembl chr11:36,492,011...36,634,216 		JBrowse link
G LTF lactotransferrin ISO RGD PMID:23201854 RGD:7243106 NCBI chr22:7,867,332...7,896,403
Ensembl chr22:7,867,286...7,894,521 		JBrowse link
G M6PR mannose-6-phosphate receptor, cation dependent ISO CTD Direct Evidence: marker/mechanism CTD PMID:23797736 NCBI chr11:8,759,490...8,769,130
Ensembl chr11:8,757,799...8,768,379 		JBrowse link
G MANF mesencephalic astrocyte derived neurotrophic factor susceptibility ISO RGD PMID:8649854 RGD:1599220 NCBI chr22:12,725,718...12,730,377
Ensembl chr22:12,726,308...12,730,587 		JBrowse link
G MAP2K1 mitogen-activated protein kinase kinase 1 ISO protein:increased expression:tumor:13/25 cases (52%)
inhibition suppressed tumor growth and vascularization in an RCC xenograft model		 RGD PMID:7664295 PMID:18172299 RGD:2292629 RGD:2292630 NCBI chr26:17,059,122...17,168,787
Ensembl chr26:17,060,054...17,168,782 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 susceptibility ISO DNA:missense mutation: :multiple RGD PMID:22517515 RGD:13504815 NCBI chr19:4,246,144...4,352,648
Ensembl chr19:4,246,122...4,353,325 		JBrowse link
G MET MET proto-oncogene, receptor tyrosine kinase ISO ClinVar Annotator: match by term: Renal adenocarcinoma | ClinVar Annotator: match by term: Renal cell carcinoma
ClinVar Annotator: match by term: Renal adenocarcinoma | ClinVar Annotator: match by term: Renal cell carcinoma | ClinVar Annotator: match by term: Renal cell carcinoma, somatic
ClinVar Annotator: match by term: Renal adenocarcinoma | ClinVar Annotator: match by term: Renal cell carcinoma | ClinVar Annotator: match by term: Renal cell carcinoma with paraneoplastic erythrocytosis | ClinVar Annotator: match by term: Renal cell carcinoma, somatic		 ClinVar PMID:1104268 PMID:9140397 PMID:9326629 PMID:9536098 PMID:9563489 More... NCBI chr21:85,370,574...85,486,405
Ensembl chr21:85,397,645...85,488,093 		JBrowse link
G MGP matrix Gla protein disease_progression ISO mRNA:increased expression:tumor:inversely related to tumor size (0.025 RGD PMID:1399132 RGD:2293578 NCBI chr11:14,776,668...14,780,796
Ensembl chr11:14,776,209...14,780,947 		JBrowse link
G MITF melanocyte inducing transcription factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:22012259 NCBI chr22:30,747,747...30,971,951
Ensembl chr22:30,748,440...30,972,168 		JBrowse link
G MLH1 mutL homolog 1 ISO protein:decreased expression:kidney RGD PMID:16426918 RGD:2293509 NCBI chr15:2,364,537...2,418,379
Ensembl chr15:2,364,738...2,418,393 		JBrowse link
G MMP1 matrix metallopeptidase 1 susceptibility
no_association		 ISO DNA:insertion:promoter:g.-1607insG (human) RGD PMID:12845675 PMID:17980059 RGD:7207023 RGD:7207082 NCBI chr 1:94,167,507...94,177,357
Ensembl chr 1:94,167,219...94,176,767 		JBrowse link
G MMP2 matrix metallopeptidase 2 disease_progression ISO mRNA:decreased expression:kidney
protein:increased expression:kidney		 RGD PMID:17572184 PMID:18035688 RGD:2290358 RGD:2290359 NCBI chr 5:41,264,382...41,291,657
Ensembl chr 5:41,264,354...41,291,004 		JBrowse link
G MMP3 matrix metallopeptidase 3 ISO DNA:missense mutation:cds:p.E45K rs679620 (human) RGD PMID:15319295 PMID:19551141 RGD:7207067 RGD:7241233 NCBI chr 1:94,216,156...94,224,437
Ensembl chr 1:94,216,173...94,224,264 		JBrowse link
G MMP9 matrix metallopeptidase 9 ISO mRNA:increased expression:kidney RGD PMID:18035688 RGD:2290358 NCBI chr 2:17,867,267...17,874,757
Ensembl chr 2:17,867,177...17,874,712 		JBrowse link
G MOK MOK protein kinase ISO mRNA:increased expression:kidney RGD PMID:15900605 RGD:7243170 NCBI chr24:80,157,374...80,233,339
Ensembl chr24:80,157,847...80,213,292 		JBrowse link
G MSGN1 mesogenin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23797736 NCBI chr14:89,852,082...89,855,540
Ensembl chr14:89,853,400...89,853,981 		JBrowse link
G MSH2 mutS homolog 2 ISO ClinVar Annotator: match by term: Renal adenocarcinoma ClinVar PMID:18325052 PMID:21926548 PMID:24506336 PMID:24763289 PMID:25637381 More... NCBI chr14:59,730,101...59,802,857
Ensembl chr14:59,729,789...59,802,819 		JBrowse link
G MTHFR methylenetetrahydrofolate reductase susceptibility ISO DNA:missense mutation:cds:p.A222V (rs1801133) (human) RGD PMID:18098291 RGD:6893654 NCBI chr20:119,987,667...120,003,611
Ensembl chr20:119,990,133...120,002,950 		JBrowse link
G MTOR mechanistic target of rapamycin kinase ISO ClinVar Annotator: match by term: Renal adenocarcinoma ClinVar PMID:20190810 PMID:22729223 PMID:24631838 PMID:25599672 PMID:25741868 More... NCBI chr20:120,522,667...120,678,988
Ensembl chr20:120,525,737...120,679,020 		JBrowse link
G MUC1 mucin 1, cell surface associated disease_progression ISO RGD PMID:10390012 RGD:7245968 NCBI chr20:8,641,701...8,646,739
Ensembl chr20:8,642,842...8,646,962 		JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor ISO protein:increased expression:kidney (rat)
mRNA:increased expression:kidney (human)		 RGD PMID:18055543 PMID:21982273 RGD:7207793 RGD:7207841 NCBI chr 8:122,282,989...122,288,392
Ensembl chr 8:122,282,630...122,288,384 		JBrowse link
G NAV3 neuron navigator 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22138691 NCBI chr11:72,891,767...73,780,924 JBrowse link
G NDRG1 N-myc downstream regulated 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15108329 NCBI chr 8:127,668,012...127,727,918
Ensembl chr 8:127,667,981...127,719,011 		JBrowse link
G NF2 NF2, moesin-ezrin-radixin like (MERLIN) tumor suppressor ISO CTD Direct Evidence: marker/mechanism
OMIM:300854		 CTD
MouseDO
RGD		 PMID:19487675 PMID:25401301 RGD:2315000 NCBI chr19:12,474,479...12,572,144
Ensembl chr19:12,474,468...12,572,250 		JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 ISO ClinVar Annotator: match by term: Renal adenocarcinoma | ClinVar Annotator: match by term: Renal cell carcinoma ClinVar PMID:26619011 NCBI chr10:62,789,647...62,825,651
Ensembl chr10:62,790,124...62,825,339 		JBrowse link
G NLRP12 NLR family pyrin domain containing 12 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23797736 NCBI chr 6:46,507,241...46,533,832
Ensembl chr 6:46,507,410...46,533,615 		JBrowse link
G NNMT nicotinamide N-methyltransferase ISO mRNA:increased expression:kidney
mRNA:increased expression:kidney (human)		 RGD PMID:15682440 PMID:17070307 RGD:2299120 RGD:401793726 NCBI chr 1:105,650,178...105,708,441
Ensembl chr 1:105,690,085...105,713,010 		JBrowse link
G NR3C1 nuclear receptor subfamily 3 group C member 1 treatment
severity		 ISO RGD PMID:18181043 PMID:21531004 RGD:7174727 RGD:7174733 NCBI chr23:45,904,926...46,031,804
Ensembl chr23:45,904,873...46,031,125 		JBrowse link
G NRAS NRAS proto-oncogene, GTPase ISO ClinVar Annotator: match by term: Renal adenocarcinoma ClinVar PMID:1654209 PMID:2278970 PMID:2674680 PMID:3122217 PMID:6587382 More... NCBI chr20:18,953,273...18,966,002
Ensembl chr20:18,953,883...18,961,931 		JBrowse link
G NRP1 neuropilin 1 disease_progression ISO RGD PMID:31880322 RGD:401901169 NCBI chr 9:32,474,787...32,632,746
Ensembl chr 9:32,474,309...32,633,101 		JBrowse link
G OGG1 8-oxoguanine DNA glycosylase ISO OMIM NCBI chr22:45,757,414...45,763,690 JBrowse link
G PAK1 p21 (RAC1) activated kinase 1 ISO CTD Direct Evidence: marker/mechanism
protein:increased expression:kidney		 CTD
RGD		 PMID:17621631 RGD:2299159 NCBI chr 1:68,530,037...68,679,413
Ensembl chr 1:68,529,571...68,617,092 		JBrowse link
G PBRM1 polybromo 1 ISO OMIM NCBI chr22:13,914,023...14,059,221
Ensembl chr22:13,913,285...14,055,254 		JBrowse link
G PCNA proliferating cell nuclear antigen severity ISO RGD PMID:11369057 RGD:2315008 NCBI chr 2:32,936,600...32,953,635
Ensembl chr 2:32,948,196...32,953,991 		JBrowse link
G PDCD1 programmed cell death 1 disease_progression ISO RGD PMID:17363529 RGD:7248680 NCBI chr10:127,877,383...127,886,234
Ensembl chr10:127,878,554...127,886,088 		JBrowse link
G PDGFRA platelet derived growth factor receptor alpha disease_progression ISO protein:increased expression:kidney RGD PMID:12866380 RGD:2292157 NCBI chr 7:14,243,291...14,307,373
Ensembl chr 7:14,241,070...14,307,422 		JBrowse link
G PDGFRB platelet derived growth factor receptor beta ISO mRNA:increased expression:kidney RGD PMID:15994946 PMID:16865223 RGD:2290496 RGD:2292198 NCBI chr23:52,724,061...52,766,264
Ensembl chr23:52,724,005...52,766,234 		JBrowse link
G PDHB pyruvate dehydrogenase E1 subunit beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:25401301 NCBI chr22:19,718,610...19,725,037
Ensembl chr22:19,718,353...19,725,036 		JBrowse link
G PDPN podoplanin disease_progression ISO RGD PMID:18291512 RGD:2292239 NCBI chr20:118,644,060...118,679,508
Ensembl chr20:118,644,051...118,679,311 		JBrowse link
G PDXDC1 pyridoxal dependent decarboxylase domain containing 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25401301 NCBI chr 5:14,293,169...14,351,453
Ensembl chr 5:14,293,429...14,351,093 		JBrowse link
G PEBP1 phosphatidylethanolamine binding protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25329396 NCBI chr11:113,469,845...113,479,177 JBrowse link
G PFAS phosphoribosylformylglycinamidine synthase ISO RGD PMID:6722784 RGD:5135276 NCBI chr16:7,618,952...7,639,700
Ensembl chr16:7,623,817...7,638,594 		JBrowse link
G PGF placental growth factor disease_progression ISO protein:increased expression:plasma RGD PMID:14981951 RGD:13506645 NCBI chr24:52,160,904...52,174,493
Ensembl chr24:52,161,787...52,173,989 		JBrowse link
G PGK1 phosphoglycerate kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15108329 NCBI chr  X:67,072,029...67,093,881 JBrowse link
G PIDD1 p53-induced death domain protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20208132 NCBI chr 1:602,594...609,388
Ensembl chr 1:602,721...607,893 		JBrowse link
G PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha ISO ClinVar Annotator: match by term: Renal adenocarcinoma
ClinVar Annotator: match by term: Renal adenocarcinoma | ClinVar Annotator: match by term: Renal cell carcinoma		 ClinVar PMID:15016963 PMID:15254419 PMID:15520168 PMID:15608678 PMID:15647370 More... NCBI chr15:10,218,034...10,304,874
Ensembl chr15:10,218,805...10,294,316 		JBrowse link
G PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 disease_progression ISO RGD PMID:25757764 RGD:13504823 NCBI chr 4:64,321,296...64,406,188
Ensembl chr 4:64,321,078...64,406,519 		JBrowse link
G PLAU plasminogen activator, urokinase severity ISO mRNA:increased expression:kidney (human) RGD PMID:20544684 RGD:7241133 NCBI chr 9:57,452,904...57,459,345
Ensembl chr 9:57,452,761...57,459,286 		JBrowse link
G PLD2 phospholipase D2 ISO protein:increased expression:kidney RGD PMID:11185526 RGD:2299898 NCBI chr16:4,283,248...4,298,034
Ensembl chr16:4,283,521...4,298,632 		JBrowse link
G PMEPA1 prostate transmembrane protein, androgen induced 1 ISO mRNA:increased expression:kidney RGD PMID:11568975 RGD:2315108 NCBI chr 2:6,403,358...6,465,958
Ensembl chr 2:6,404,515...6,465,982 		JBrowse link
G PNKD PNKD metallo-beta-lactamase domain containing ISO CTD Direct Evidence: marker/mechanism CTD PMID:25401301 NCBI chr10:104,152,005...104,227,624
Ensembl chr10:104,152,081...104,229,219 		JBrowse link
G POMC proopiomelanocortin ISO CTD Direct Evidence: marker/mechanism CTD PMID:2844640 NCBI chr14:82,491,296...82,499,289
Ensembl chr14:82,494,323...82,499,447 		JBrowse link
G PPAT phosphoribosyl pyrophosphate amidotransferase ISO protein:increased activity:tumor (rat) RGD PMID:476627 RGD:5135050 NCBI chr 7:12,201,434...12,242,418
Ensembl chr 7:12,191,784...12,243,488 		JBrowse link
G PRCC proline rich mitotic checkpoint control factor ISO ClinVar Annotator: match by term: Renal cell carcinoma, somatic ClinVar PMID:25741868 NCBI chr20:7,068,711...7,099,745
Ensembl chr20:7,068,333...7,099,339 		JBrowse link
G PSMB9 proteasome 20S subunit beta 9 ISO DNA:snp:promoter:g.-151G>T (human) RGD PMID:11788900 RGD:9999148 NCBI chr17:39,246,356...39,251,852
Ensembl chr17:39,245,854...39,251,842 		JBrowse link
G PTEN phosphatase and tensin homolog disease_progression ISO ClinVar Annotator: match by term: Renal adenocarcinoma
ClinVar Annotator: match by term: Renal adenocarcinoma | ClinVar Annotator: match by term: Renal cell carcinoma		 RGD
ClinVar		 PMID:1945792 PMID:9467011 PMID:9915974 PMID:10866302 PMID:11051241 More... RGD:2292513 NCBI chr 9:81,308,058...81,412,386
Ensembl chr 9:81,309,099...81,409,146 		JBrowse link
G PTGS1 prostaglandin-endoperoxide synthase 1 ISO mRNA:increased expression:kidney RGD PMID:12708469 RGD:2300212 NCBI chr12:17,195,403...17,218,450
Ensembl chr12:17,192,628...17,218,315 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 disease_progression ISO mRNA:decreased expression:kidney
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:12664575 PMID:12708469 PMID:17899436 RGD:2300204 RGD:2300212 NCBI chr25:42,733,535...42,742,463
Ensembl chr25:42,734,771...42,742,429 		JBrowse link
G PVALB parvalbumin ISO CTD Direct Evidence: marker/mechanism CTD PMID:16927643 NCBI chr19:19,501,100...19,520,031
Ensembl chr19:19,501,293...19,517,340 		JBrowse link
G RASSF1 Ras association domain family member 1 ISO DNA:hypermethylation:promoter RGD PMID:17645803 RGD:2299866 NCBI chr22:11,716,969...11,728,646
Ensembl chr22:11,716,918...11,725,027 		JBrowse link
G RB1 RB transcriptional corepressor 1 disease_progression ISO RGD PMID:11549509 RGD:2299893 NCBI chr 3:26,220,783...26,393,671
Ensembl chr 3:26,220,803...26,394,546 		JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit ISO protein:increased expression:kidney
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:12663495 PMID:17290398 PMID:18089796 RGD:2298755 RGD:2298771 NCBI chr 1:8,576,059...8,585,561
Ensembl chr 1:8,576,542...8,586,516 		JBrowse link
G RHEB Ras homolog, mTORC1 binding ISO ClinVar Annotator: match by term: Renal adenocarcinoma ClinVar PMID:26619011 NCBI chr21:119,652,692...119,704,833
Ensembl chr21:119,652,127...119,703,458 		JBrowse link
G RNF139 ring finger protein 139 ISO OMIM NCBI chr 8:119,041,885...119,055,119
Ensembl chr 8:119,042,223...119,054,486 		JBrowse link
G RPL14 ribosomal protein L14 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23797736 NCBI chr22:1,949,789...1,954,518
Ensembl chr22:1,949,817...1,954,466 		JBrowse link
G RYR1 ryanodine receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22138691 NCBI chr 6:33,080,443...33,234,478
Ensembl chr 6:33,080,758...33,213,788 		JBrowse link
G SCARB1 scavenger receptor class B member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21131975 NCBI chr11:120,134,485...120,223,512
Ensembl chr11:120,134,874...120,216,904 		JBrowse link
G SDHB succinate dehydrogenase complex iron sulfur subunit B ISO ClinVar Annotator: match by term: Renal adenocarcinoma | ClinVar Annotator: match by term: Renal cell carcinoma ClinVar PMID:18728283 PMID:19576851 PMID:22835832 PMID:24055113 PMID:24092654 More... NCBI chr20:115,537,880...115,571,150
Ensembl chr20:115,538,026...115,571,142 		JBrowse link
G SETD2 SET domain containing 2, histone lysine methyltransferase ISO CTD Direct Evidence: marker/mechanism CTD PMID:22138691 PMID:23797736 NCBI chr22:8,421,178...8,567,221
Ensembl chr22:8,420,960...8,567,201 		JBrowse link
G SF3B1 splicing factor 3b subunit 1 ISO ClinVar Annotator: match by term: Renal adenocarcinoma ClinVar PMID:26619011 NCBI chr10:82,901,908...82,952,094
Ensembl chr10:82,899,079...82,952,071 		JBrowse link
G SF3B2 splicing factor 3b subunit 2 ISO ClinVar Annotator: match by term: Renal adenocarcinoma ClinVar PMID:26619011 NCBI chr 1:8,189,636...8,207,024
Ensembl chr 1:8,189,446...8,207,020 		JBrowse link
G SFRP1 secreted frizzled related protein 1 ISO mRNA:decreased expression:kidney RGD PMID:20420713 RGD:4107084 NCBI chr 8:39,243,775...39,289,050
Ensembl chr 8:39,243,780...39,288,984 		JBrowse link
G SFRP2 secreted frizzled related protein 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18404682 NCBI chr 7:100,336,442...100,345,093
Ensembl chr 7:100,336,119...100,345,086 		JBrowse link
G SHANK1 SH3 and multiple ankyrin repeat domains 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22138691 NCBI chr 6:43,718,904...43,776,814
Ensembl chr 6:43,716,714...43,773,945 		JBrowse link
G SKP2 S-phase kinase associated protein 2 disease_progression ISO RGD PMID:18922157 RGD:2315038 NCBI chr 4:35,009,114...35,040,518
Ensembl chr 4:35,009,076...35,042,632 		JBrowse link
G SLC2A1 solute carrier family 2 member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:7921415 NCBI chr20:89,974,567...90,007,977
Ensembl chr20:90,002,030...90,008,033 		JBrowse link
G SLC49A4 solute carrier family 49 member 4 susceptibility ISO DNA:translocation:intron:t(2;3)(q35;q21) RGD PMID:11912179 RGD:1601072 NCBI chr22:57,998,168...58,080,900
Ensembl chr22:57,998,708...58,081,270 		JBrowse link
G SLC5A3 solute carrier family 5 member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25401301 NCBI chr 2:58,104,938...58,131,225 JBrowse link
G SMAD2 SMAD family member 2 severity ISO protein:decreased expression:kidney RGD PMID:11332076 RGD:2299973 NCBI chr18:33,017,138...33,105,320
Ensembl chr18:33,017,492...33,104,606 		JBrowse link
G SMAD4 SMAD family member 4 severity ISO protein:decreased expression:kidney RGD PMID:11332076 RGD:2299973 NCBI chr18:29,894,157...29,951,445
Ensembl chr18:29,897,621...29,934,478 		JBrowse link
G SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1 disease_progression ISO RGD PMID:33532313 RGD:127285652 NCBI chr22:8,987,936...9,167,689
Ensembl chr22:8,987,012...9,134,946 		JBrowse link
G SOD2 superoxide dismutase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15108329 NCBI chr13:87,284,537...87,297,998
Ensembl chr13:87,280,686...87,297,974 		JBrowse link
G SPARC secreted protein acidic and cysteine rich ISO mRNA, protein:increased expression:kidney RGD PMID:11679940 RGD:2300025 NCBI chr23:54,224,003...54,248,869
Ensembl chr23:54,222,838...54,238,006 		JBrowse link
G SPINK1 serine peptidase inhibitor Kazal type 1 disease_progression ISO protein:increased expression:serum
protein:decreased expression:kidney		 RGD PMID:10508484 PMID:11176522 RGD:2300387 RGD:2300388 NCBI chr23:50,365,686...50,373,300
Ensembl chr23:50,365,269...50,372,814 		JBrowse link
G SPTBN4 spectrin beta, non-erythrocytic 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22138691 NCBI chr 6:34,926,413...35,036,611
Ensembl chr 6:34,930,519...35,035,719 		JBrowse link
G ST14 ST14 transmembrane serine protease matriptase ISO protein:increased expression:kidney RGD PMID:16501837 RGD:2315090 NCBI chr 1:121,238,666...121,290,528
Ensembl chr 1:121,238,643...121,290,007 		JBrowse link
G ST7 suppression of tumorigenicity 7 ISO ClinVar Annotator: match by term: Renal adenocarcinoma | ClinVar Annotator: match by term: Renal cell carcinoma | ClinVar Annotator: match by term: Renal cell carcinoma, somatic ClinVar PMID:28492532 NCBI chr21:85,632,652...85,908,772
Ensembl chr21:85,632,792...85,909,049 		JBrowse link
G STAT3 signal transducer and activator of transcription 3 disease_progression ISO DNA:snp
protein:increased phosphorylation:kidney		 RGD PMID:12131365 PMID:17602083 RGD:2291913 RGD:2291917 NCBI chr16:63,877,884...63,957,894
Ensembl chr16:63,922,862...63,957,984 		JBrowse link
G SYNE2 spectrin repeat containing nuclear envelope protein 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22138691 NCBI chr24:41,054,609...41,443,067
Ensembl chr24:41,054,621...41,443,436 		JBrowse link
G TAGLN2 transgelin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15108329 NCBI chr20:4,024,948...4,032,361
Ensembl chr20:4,024,775...4,032,526 		JBrowse link
G TERT telomerase reverse transcriptase ISO mRNA, protein:increased expression:kidney RGD PMID:18250061 RGD:2291980 NCBI chr 4:1,082,894...1,119,373
Ensembl chr 4:1,083,384...1,117,468 		JBrowse link
G TET2 tet methylcytosine dioxygenase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23797736 NCBI chr 7:53,193,824...53,326,813
Ensembl chr 7:53,193,941...53,326,942 		JBrowse link
G TFE3 transcription factor binding to IGHM enhancer 3 ISO CTD Direct Evidence: marker/mechanism RGD
CTD		 PMID:12917640 RGD:1599384 NCBI chr  X:46,141,377...46,155,445
Ensembl chr  X:46,140,543...46,155,372 		JBrowse link
G TFRC transferrin receptor ISO mRNA:decreased expression:kidney, T cell
protein:increased expression:kidney, T cell		 RGD PMID:8050820 PMID:12394762 RGD:2292024 RGD:2292025 NCBI chr15:91,102,153...91,134,994
Ensembl chr15:91,102,817...91,135,584 		JBrowse link
G TGFB1 transforming growth factor beta 1 disease_progression ISO protein:increased expression:peripheral blood RGD PMID:25499257 PMID:26631499 PMID:26749573 RGD:11560966 RGD:13506173 RGD:13506175 NCBI chr 6:35,651,583...35,674,387
Ensembl chr 6:35,648,677...35,674,365 		JBrowse link
G TGM2 transglutaminase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15108329 NCBI chr 2:25,585,827...25,623,961
Ensembl chr 2:25,585,865...25,624,280 		JBrowse link
G THRA thyroid hormone receptor alpha ISO DNA:mutations (human) RGD PMID:11756220 RGD:2315097 NCBI chr16:66,087,071...66,118,137 JBrowse link
G THRB thyroid hormone receptor beta ISO DNA:mutations (human) RGD PMID:11756220 RGD:2315097 NCBI chr15:68,797,410...69,161,256
Ensembl chr15:68,802,078...68,902,292 		JBrowse link
G TIMP1 TIMP metallopeptidase inhibitor 1 disease_progression ISO protein:increased expression:kidney RGD PMID:11595703 RGD:2290350
G TIMP2 TIMP metallopeptidase inhibitor 2 disease_progression ISO protein:increased expression:kidney
mRNA:decreased expression:kidney		 RGD PMID:17572184 PMID:18035688 RGD:2290358 RGD:2290359 NCBI chr16:70,819,591...70,850,471
Ensembl chr16:70,819,139...70,850,471 		JBrowse link
G TIMP3 TIMP metallopeptidase inhibitor 3 ISO mRNA:decreased expression:kidney RGD PMID:11576837 RGD:2290421 NCBI chr19:15,621,609...15,684,118
Ensembl chr19:15,622,431...15,680,449 		JBrowse link
G TIMP4 TIMP metallopeptidase inhibitor 4 ISO mRNA:decreased expression:kidney RGD PMID:11576837 RGD:2290421 NCBI chr22:48,134,133...48,140,870
Ensembl chr22:48,134,637...48,140,600 		JBrowse link
G TNF tumor necrosis factor ISO RGD PMID:19384924 PMID:19904265 RGD:2315113 RGD:2315119
G TNFRSF10A TNF receptor superfamily member 10a ISO mRNA:increased expression:kidney RGD PMID:16865223 PMID:17184908 RGD:2290491 RGD:2290496 NCBI chr 8:21,318,987...21,351,641
Ensembl chr 8:21,315,149...21,351,673 		JBrowse link
G TNFRSF1A TNF receptor superfamily member 1A ISO protein:increased expression:serum (human) RGD PMID:7912320 RGD:5131437 NCBI chr11:6,364,544...6,378,880
Ensembl chr11:6,364,330...6,378,902 		JBrowse link
G TNFRSF1B TNF receptor superfamily member 1B ISO RGD PMID:20566746 RGD:7245512 NCBI chr20:119,590,621...119,633,562
Ensembl chr20:119,590,325...119,633,497 		JBrowse link
G TNFSF10 TNF superfamily member 10 ISO CTD Direct Evidence: therapeutic CTD PMID:20403343 NCBI chr15:16,934,982...16,953,155
Ensembl chr15:16,934,962...16,954,860 		JBrowse link
G TP53 tumor protein p53 disease_progression ISO ClinVar Annotator: match by term: Renal adenocarcinoma | ClinVar Annotator: match by term: Renal cell carcinoma
ClinVar Annotator: match by term: Renal adenocarcinoma | ClinVar Annotator: match by term: Renal cell carcinoma | ClinVar Annotator: match by term: Renal cell carcinoma, somatic		 RGD
ClinVar		 PMID:253702 PMID:960674 PMID:1349175 PMID:1565143 PMID:1565144 More... RGD:2290544 NCBI chr16:7,047,686...7,065,567
Ensembl chr16:7,045,146...7,066,223 		JBrowse link
G TP73 tumor protein p73 ISO RGD PMID:9796703 RGD:2291837 NCBI chr20:127,958,002...128,035,792
Ensembl chr20:127,958,809...128,013,691 		JBrowse link
G TSC1 TSC complex subunit 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22138691 NCBI chr12:5,195,604...5,249,042
Ensembl chr12:5,195,675...5,244,157 		JBrowse link
G TSC2 TSC complex subunit 2 treatment ISO DNA:nonsense mutations;missense mutations; splice-site mutation:multiple RGD PMID:10029074 PMID:10096549 PMID:18695678 RGD:11568655 RGD:11568661 RGD:68666 NCBI chr 5:1,946,534...1,985,168
Ensembl chr 5:1,946,927...1,987,682 		JBrowse link
G TXNIP thioredoxin interacting protein ISO DNA, mRNA, protein:hypermethylation, decreased expression:promoter, kidney RGD PMID:15834431 RGD:1642756 NCBI chr20:12,756,145...12,759,853
Ensembl chr20:12,756,053...12,761,177 		JBrowse link
G TYMP thymidine phosphorylase severity ISO protein:increased expression:kidney RGD PMID:12614261 PMID:16861722 RGD:2293717 RGD:2293723 NCBI chr19:32,997,337...33,001,558
Ensembl chr19:32,997,304...33,001,215 		JBrowse link
G UNC5C unc-5 netrin receptor C ISO CTD Direct Evidence: marker/mechanism CTD PMID:21600761 NCBI chr 7:43,405,666...43,786,436 JBrowse link
G VEGFA vascular endothelial growth factor A disease_progression ISO RGD PMID:19755989 RGD:2315455 NCBI chr17:28,377,959...28,394,508 JBrowse link
G VEGFC vascular endothelial growth factor C ISO RGD PMID:19500329 RGD:2315476 NCBI chr 7:122,772,539...122,893,486
Ensembl chr 7:122,772,182...122,893,512 		JBrowse link
G VHL von Hippel-Lindau tumor suppressor ISO ClinVar Annotator: match by term: Renal adenocarcinoma | ClinVar Annotator: match by term: Renal cell carcinoma with paraneoplastic erythrocytosis OMIM
ClinVar		 PMID:7563486 PMID:7660122 PMID:7728151 PMID:7784063 PMID:7977367 More... NCBI chr22:46,184,621...46,203,065
Ensembl chr22:46,184,756...46,204,428 		JBrowse link
G VMO1 vitelline membrane outer layer 1 homolog ISO CTD Direct Evidence: marker/mechanism CTD PMID:23797736 NCBI chr16:4,261,009...4,262,174
Ensembl chr16:4,261,012...4,262,168 		JBrowse link
G VWF von Willebrand factor disease_progression ISO protein:increased expression:plasma RGD PMID:21953673 RGD:7207032 NCBI chr11:5,994,499...6,176,949
Ensembl chr11:5,994,039...6,162,260 		JBrowse link
G WIF1 WNT inhibitory factor 1 ISO DNA:hypermethylation:promoter RGD PMID:17145819 RGD:2291869 NCBI chr11:60,728,316...60,800,181
Ensembl chr11:60,727,948...60,799,960 		JBrowse link
G WNT11 Wnt family member 11 ISO mRNA:increased expression:tumor:increased in a single case RGD PMID:11712081 RGD:2299947 NCBI chr 1:67,393,975...67,427,247
Ensembl chr 1:67,399,074...67,418,509 		JBrowse link
G WNT2 Wnt family member 2 ISO ClinVar Annotator: match by term: Renal adenocarcinoma | ClinVar Annotator: match by term: Renal cell carcinoma | ClinVar Annotator: match by term: Renal cell carcinoma, somatic ClinVar PMID:28492532 NCBI chr21:85,955,517...86,005,664
Ensembl chr21:85,955,145...86,001,730 		JBrowse link
G XIAP X-linked inhibitor of apoptosis disease_progression ISO protein:increased expression:kidney RGD PMID:17332931 RGD:2315854
G XRCC1 X-ray repair cross complementing 1 susceptibility ISO DNA:SNP: :p.R399Q RGD PMID:16510122 RGD:2302577 NCBI chr 6:37,062,149...37,095,138
Ensembl chr 6:37,060,439...37,095,094 		JBrowse link
G YIPF3 Yip1 domain family member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23797736 NCBI chr17:28,642,405...28,647,565
Ensembl chr17:28,642,586...28,647,273 		JBrowse link
G ZNF536 zinc finger protein 536 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23797736 NCBI chr 6:25,275,439...25,759,834
Ensembl chr 6:25,494,973...25,599,359 		JBrowse link
G ZNF804A zinc finger protein 804A ISO CTD Direct Evidence: marker/mechanism CTD PMID:22138691 NCBI chr10:70,094,213...70,431,682 JBrowse link
chromophobe renal cell carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BIRC5 baculoviral IAP repeat containing 5 exacerbates ISO mRNA:increased expression:kidney (human) RGD PMID:31964418 RGD:153344516 NCBI chr16:70,226,824...70,237,000 JBrowse link
G HNF1A HNF1 homeobox A ISO ClinVar Annotator: match by term: Chromophobe renal cell carcinoma ClinVar PMID:9392505 PMID:9754819 PMID:10966642 PMID:11393552 PMID:15649945 More... NCBI chr11:116,334,935...116,358,582
Ensembl chr11:116,335,675...116,357,751 		JBrowse link
G HNF1B HNF1 homeobox B ISO ClinVar Annotator: match by term: Chromophobe renal cell carcinoma ClinVar PMID:15649945 PMID:16371430 PMID:25536396 PMID:25700310 PMID:25741868 NCBI chr16:30,033,486...30,097,106
Ensembl chr16:30,036,766...30,097,088 		JBrowse link
clear cell renal cell carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACKR3 atypical chemokine receptor 3 ISO mRNA:increased expression:kidney: RGD PMID:29218250 RGD:155804290 NCBI chr10:122,558,998...122,573,747
Ensembl chr10:122,571,853...122,572,941 		JBrowse link
G AGER advanced glycosylation end-product specific receptor ISO mRNA:increased expression:renal cortex (human) RGD PMID:21947243 RGD:7244181 NCBI chr17:39,847,343...39,851,288
Ensembl chr17:39,847,759...39,851,127 		JBrowse link
G ATM ATM serine/threonine kinase ISO ClinVar Annotator: match by term: Clear cell carcinoma of kidney ClinVar PMID:8755918 PMID:9792409 PMID:10980530 PMID:18560558 PMID:19431188 More... NCBI chr 1:99,653,208...99,786,889
Ensembl chr 1:99,653,139...99,791,520 		JBrowse link
G ATP5MC2 ATP synthase membrane subunit c locus 2 ISO RGD PMID:28672194 RGD:14696810 NCBI chr11:49,768,977...49,780,664
Ensembl chr11:49,768,783...49,780,081 		JBrowse link
G ATP5PB ATP synthase peripheral stalk-membrane subunit b ISO RGD PMID:28672194 RGD:14696810 NCBI chr20:22,150,488...22,162,740
Ensembl chr20:22,150,239...22,162,312 		JBrowse link
G ATP5PO ATP synthase peripheral stalk subunit OSCP ISO RGD PMID:28672194 RGD:14696810 NCBI chr 2:58,273,181...58,285,615 JBrowse link
G BAP1 BRCA1 associated protein 1 ISO ClinVar Annotator: match by term: Clear cell carcinoma of kidney ClinVar PMID:25741868 PMID:28492532 PMID:35483881 PMID:35992853 NCBI chr22:13,765,510...13,774,866
Ensembl chr22:13,764,686...13,774,740 		JBrowse link
G BAX BCL2 associated X, apoptosis regulator ISO mRNA, protein:increased expression:kidney RGD PMID:28551630 RGD:15036804 NCBI chr 6:42,186,028...42,193,105 JBrowse link
G BIRC3 baculoviral IAP repeat containing 3 disease_progression ISO mRNA:increased expression:kidney (human) RGD PMID:31964418 RGD:153344516 NCBI chr 1:93,692,239...93,711,905 JBrowse link
G BIRC5 baculoviral IAP repeat containing 5 exacerbates ISO mRNA:increased expression:kidney (human) RGD PMID:31964418 RGD:153344516 NCBI chr16:70,226,824...70,237,000 JBrowse link
G BIRC6 baculoviral IAP repeat containing 6 ameliorates ISO mRNA:increased expression:kidney (human) RGD PMID:31964418 RGD:153344516 NCBI chr14:74,879,597...75,138,462
Ensembl chr14:74,878,700...75,138,441 		JBrowse link
G CHD4 chromodomain helicase DNA binding protein 4 ISO mRNA:decreased expression:kidney (human) RGD PMID:28486105 RGD:153323299 NCBI chr11:6,603,820...6,641,278
Ensembl chr11:6,602,694...6,640,351 		JBrowse link
G CUNH11orf65 chromosome unknown C11orf65 homolog ISO ClinVar Annotator: match by term: Clear cell carcinoma of kidney ClinVar PMID:8755918 PMID:9792409 PMID:10980530 PMID:18560558 PMID:19431188 More... NCBI chr 1:99,804,191...99,879,834
Ensembl chr 1:99,804,218...99,827,182 		JBrowse link
G CXCL12 C-X-C motif chemokine ligand 12 ISO mRNA:decreased expression:kidney: RGD PMID:29218250 RGD:155804290 NCBI chr 9:40,005,580...40,020,513
Ensembl chr 9:40,011,439...40,020,494 		JBrowse link
G CXCR4 C-X-C motif chemokine receptor 4 ISO mRNA:increased expression:kidney: RGD PMID:29218250 RGD:155804290 NCBI chr10:20,336,470...20,340,308
Ensembl chr10:20,336,247...20,340,309 		JBrowse link
G DDR1 discoidin domain receptor tyrosine kinase 1 severity ISO mRNA, protein:decreased expression:kidney (human)
mRNA:increased expression:kidney, lymph nodes (human)		 RGD PMID:27020590 PMID:31018949 RGD:151347528 RGD:151347863 NCBI chr17:41,564,271...41,583,404
Ensembl chr17:41,564,992...41,575,682 		JBrowse link
G DNMT1 DNA methyltransferase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27292127 NCBI chr 6:9,199,006...9,263,890
Ensembl chr 6:9,199,003...9,263,607 		JBrowse link
G DNMT3A DNA methyltransferase 3 alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:27292127 NCBI chr14:82,313,414...82,427,170
Ensembl chr14:82,402,826...82,420,819 		JBrowse link
G ENG endoglin severity ISO protein:decreased expression:kidney, tumor (human)
protein:increased expression:tumor, vasculature (human)		 RGD PMID:16536758 PMID:22204709 RGD:7248775 RGD:7248780 NCBI chr12:10,274,705...10,315,715
Ensembl chr12:10,275,064...10,315,040 		JBrowse link
G EP300 E1A binding protein p300 severity ISO mRNA, protein:increased expression:kidney
mRNA:altered expression:kidney, tumor (human)		 RGD PMID:23029358 PMID:28551630 RGD:15036804 RGD:7296925 NCBI chr19:23,634,132...23,726,095
Ensembl chr19:23,634,571...23,724,979 		JBrowse link
G FLT4 fms related receptor tyrosine kinase 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25239121 NCBI chr23:82,328,257...82,373,785
Ensembl chr23:82,328,258...82,357,044 		JBrowse link
G FTO FTO alpha-ketoglutarate dependent dioxygenase treatment
disease_progression		 ISO mRNA:increased expression:kidney
mRNA:decreased expression:kidney		 RGD PMID:30648791 PMID:32817424 RGD:329812005 RGD:329812006 NCBI chr 5:39,487,304...39,900,238
Ensembl chr 5:39,487,418...39,725,747 		JBrowse link
G GATA1 GATA binding protein 1 disease_progression ISO RGD PMID:25230694 RGD:149735195 NCBI chr  X:45,912,638...45,920,415
Ensembl chr  X:45,917,231...45,920,268 		JBrowse link
G GATA2 GATA binding protein 2 disease_progression ISO RGD PMID:25230694 RGD:149735195 NCBI chr22:52,549,112...52,562,911
Ensembl chr22:52,555,738...52,562,909 		JBrowse link
G GSTP1 glutathione S-transferase pi 1 ISO RGD PMID:10383153 RGD:6906878 NCBI chr 1:6,676,897...6,679,936 JBrowse link
G HNF1A HNF1 homeobox A ISO ClinVar Annotator: match by term: Clear cell carcinoma of kidney ClinVar PMID:8866553 PMID:8945470 PMID:9032114 PMID:9045858 PMID:9075818 More... NCBI chr11:116,334,935...116,358,582
Ensembl chr11:116,335,675...116,357,751 		JBrowse link
G IGF1R insulin like growth factor 1 receptor ISO xenograph of human clear cell renal cancer cells in mouse RGD PMID:19509240 RGD:7242921 NCBI chr29:17,212,206...17,534,036
Ensembl chr29:17,459,404...17,526,930 		JBrowse link
G ISCU iron-sulfur cluster assembly enzyme disease_progression ISO mRNA,protein:decreased expression:kidney (human) RGD PMID:23449350 RGD:155260320 NCBI chr11:103,753,175...103,760,168
Ensembl chr11:103,753,189...103,760,364 		JBrowse link
G KAT8 lysine acetyltransferase 8 ISO mRNA, protein:decreased expression:kidney (human) RGD PMID:23394073 RGD:9586034 NCBI chr 5:27,806,082...27,820,832
Ensembl chr 5:27,805,844...27,820,748 		JBrowse link
G MAP3K8 mitogen-activated protein kinase kinase kinase 8 disease_progression
ameliorates		 ISO RGD PMID:23982215 RGD:151356974
G MMP12 matrix metallopeptidase 12 ISO RGD PMID:11576837 RGD:2290421 NCBI chr 1:94,243,061...94,261,035
Ensembl chr 1:94,243,875...94,259,591 		JBrowse link
G MTHFR methylenetetrahydrofolate reductase severity
susceptibility		 ISO DNA:transition, transversion:cds:g.677C>T, g.1298A>C (human) RGD PMID:20039875 PMID:21489764 RGD:6893474 RGD:6893632 NCBI chr20:119,987,667...120,003,611
Ensembl chr20:119,990,133...120,002,950 		JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor severity ISO protein:increased expression:kidney (human) RGD PMID:21881486 RGD:7207420 NCBI chr 8:122,282,989...122,288,392
Ensembl chr 8:122,282,630...122,288,384 		JBrowse link
G OGG1 8-oxoguanine DNA glycosylase ISO ClinVar Annotator: match by term: Clear cell carcinoma of kidney ClinVar PMID:9681819 PMID:10987279 PMID:12172214 PMID:19537786 PMID:21195604 More... NCBI chr22:45,757,414...45,763,690 JBrowse link
G PAK4 p21 (RAC1) activated kinase 4 disease_progression ISO RGD PMID:25744653 RGD:13504816 NCBI chr 6:33,715,695...33,769,272
Ensembl chr 6:33,759,462...33,770,497 		JBrowse link
G PAK6 p21 (RAC1) activated kinase 6 disease_progression ISO RGD PMID:24715215 RGD:13506722 NCBI chr26:42,737,848...42,798,960
Ensembl chr26:42,737,613...42,750,248 		JBrowse link
G PBRM1 polybromo 1 ISO ClinVar Annotator: match by term: Clear cell carcinoma of kidney ClinVar PMID:25911086 NCBI chr22:13,914,023...14,059,221
Ensembl chr22:13,913,285...14,055,254 		JBrowse link
G PDGFB platelet derived growth factor subunit B disease_progression ISO RGD PMID:23879920 PMID:25766258 RGD:13504817 RGD:13506650 NCBI chr19:21,865,792...21,888,068
Ensembl chr19:21,863,768...21,886,395 		JBrowse link
G PML PML nuclear body scaffold ISO protein:decreased expression:kidney (human) RGD PMID:25293974 RGD:41404694 NCBI chr26:9,441,998...9,494,949
Ensembl chr26:9,451,112...9,494,931 		JBrowse link
G PPBP pro-platelet basic protein disease_progression
ameliorates		 ISO RGD PMID:24335961 RGD:401794956 NCBI chr 7:22,470,670...22,471,841
Ensembl chr 7:22,470,573...22,471,809 		JBrowse link
G SETD2 SET domain containing 2, histone lysine methyltransferase severity ISO DNA:SNPs,loss of heterozygosity:multiple (human)
DNA:mutations:multiple (human)		 RGD PMID:26864202 PMID:26891804 RGD:150429635 RGD:150429640 NCBI chr22:8,421,178...8,567,221
Ensembl chr22:8,420,960...8,567,201 		JBrowse link
G SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 ISO mRNA,protein:decreased expression:kidney: RGD PMID:29218250 RGD:155804290 NCBI chr19:6,902,985...6,945,111
Ensembl chr19:6,902,951...6,944,784 		JBrowse link
G SRSF1 serine and arginine rich splicing factor 1 ISO mRNA:altered expression:kidney (human) RGD PMID:21082031 RGD:11039407 NCBI chr16:35,392,573...35,396,815
Ensembl chr16:35,392,873...35,394,982 		JBrowse link
G SRSF2 serine and arginine rich splicing factor 2 ISO mRNA:altered expression:kidney (human) RGD PMID:21082031 RGD:11039407 NCBI chr16:44,945,193...44,948,496
Ensembl chr16:44,945,200...44,946,438 		JBrowse link
G SRSF4 serine and arginine rich splicing factor 4 ISO mRNA:altered expression:kidney (human) RGD PMID:21082031 RGD:11039407 NCBI chr20:103,641,650...103,674,066
Ensembl chr20:103,642,150...103,673,391 		JBrowse link
G SRSF5 serine and arginine rich splicing factor 5 ISO mRNA:altered expression:kidney (human) RGD PMID:21082031 RGD:11039407 NCBI chr24:47,009,211...47,014,108
Ensembl chr24:47,009,122...47,013,644 		JBrowse link
G SRSF6 serine and arginine rich splicing factor 6 ISO mRNA:altered expression:kidney (human) RGD PMID:21082031 RGD:11039407 NCBI chr 2:20,340,163...20,345,873
Ensembl chr 2:20,342,681...20,346,122 		JBrowse link
G SRSF7 serine and arginine rich splicing factor 7 ISO mRNA:altered expression:kidney (human) RGD PMID:21082031 RGD:11039407 NCBI chr14:68,629,812...68,636,958 JBrowse link
G TP53 tumor protein p53 ISO mRNA, protein:increased expression:kidney RGD PMID:28551630 RGD:15036804 NCBI chr16:7,047,686...7,065,567
Ensembl chr16:7,045,146...7,066,223 		JBrowse link
G VEGFA vascular endothelial growth factor A ISO CTD Direct Evidence: marker/mechanism CTD PMID:25239121 NCBI chr17:28,377,959...28,394,508 JBrowse link
G XIAP X-linked inhibitor of apoptosis ameliorates ISO mRNA:increased expression:kidney (human) RGD PMID:31964418 RGD:153344516
hereditary renal cell carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DNASE1 deoxyribonuclease 1 ISO ClinVar Annotator: match by term: Hereditary renal cell carcinoma ClinVar PMID:28492532 NCBI chr 5:3,310,853...3,352,483
Ensembl chr 5:3,310,824...3,339,870 		JBrowse link
G EGF epidermal growth factor ISO ClinVar Annotator: match by term: Hereditary renal cell carcinoma ClinVar NCBI chr 7:57,810,110...57,911,361
Ensembl chr 7:57,811,728...57,911,516 		JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 ISO ClinVar Annotator: match by term: Hereditary renal cell carcinoma ClinVar NCBI chr25:3,350,798...3,405,040 JBrowse link
G SDHA succinate dehydrogenase complex flavoprotein subunit A ISO ClinVar Annotator: match by term: Hereditary renal cell carcinoma ClinVar PMID:25741868 PMID:26467025 PMID:28492532 PMID:28546994 PMID:30680959 More... NCBI chr 4:163,726...190,145 JBrowse link
G TRAP1 TNF receptor associated protein 1 ISO ClinVar Annotator: match by term: Hereditary renal cell carcinoma ClinVar PMID:28492532 NCBI chr 5:3,339,954...3,405,218
Ensembl chr 5:3,340,040...3,405,166 		JBrowse link
nonpapillary renal cell carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CAMK1 calcium/calmodulin dependent protein kinase I ISO ClinVar Annotator: match by term: Nonpapillary renal cell carcinoma ClinVar NCBI chr22:45,763,799...45,776,792
Ensembl chr22:45,762,499...45,774,597 		JBrowse link
G FLCN folliculin ISO ClinVar Annotator: match by term: Nonpapillary renal cell carcinoma ClinVar PMID:12204536 PMID:12471204 PMID:15852235 PMID:16199547 PMID:17496196 More... NCBI chr16:16,245,840...16,271,465
Ensembl chr16:16,245,715...16,267,698 		JBrowse link
G HNF1A HNF1 homeobox A ISO ClinVar Annotator: match by term: Nonpapillary renal cell carcinoma ClinVar PMID:8945470 PMID:9112026 PMID:9133564 PMID:9287053 PMID:9604876 More... NCBI chr11:116,334,935...116,358,582
Ensembl chr11:116,335,675...116,357,751 		JBrowse link
G HNF1B HNF1 homeobox B ISO ClinVar Annotator: match by term: Nonpapillary renal cell carcinoma ClinVar PMID:9398836 PMID:12148114 PMID:12161522 PMID:15068978 PMID:15930087 More... NCBI chr16:30,033,486...30,097,106
Ensembl chr16:30,036,766...30,097,088 		JBrowse link
G OGG1 8-oxoguanine DNA glycosylase ISO ClinVar Annotator: match by term: Nonpapillary renal cell carcinoma ClinVar NCBI chr22:45,757,414...45,763,690 JBrowse link
G VHL von Hippel-Lindau tumor suppressor ISO ClinVar Annotator: match by term: Nonpapillary renal cell carcinoma ClinVar PMID:7660122 PMID:7728151 PMID:7784063 PMID:7987306 PMID:8270255 More... NCBI chr22:46,184,621...46,203,065
Ensembl chr22:46,184,756...46,204,428 		JBrowse link
papillary renal cell carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BIRC3 baculoviral IAP repeat containing 3 exacerbates ISO mRNA:increased expression:kidney (human) RGD PMID:31964418 RGD:153344516 NCBI chr 1:93,692,239...93,711,905 JBrowse link
G BIRC5 baculoviral IAP repeat containing 5 disease_progression ISO mRNA:increased expression:kidney (human) RGD PMID:31964418 RGD:153344516 NCBI chr16:70,226,824...70,237,000 JBrowse link
G BRAF B-Raf proto-oncogene, serine/threonine kinase ISO ClinVar Annotator: match by term: Papillary renal cell carcinoma, sporadic | ClinVar Annotator: match by term: Renal cell carcinoma, papillary, 1 ClinVar PMID:12068308 PMID:12198537 PMID:12447372 PMID:12460918 PMID:12460919 More... NCBI chr21:109,495,525...109,690,261 JBrowse link
G ERBB2 erb-b2 receptor tyrosine kinase 2 ISO ClinVar Annotator: match by term: Papillary renal cell carcinoma, sporadic ClinVar PMID:18413839 PMID:22046346 PMID:23220880 PMID:25157968 PMID:26619011 NCBI chr16:66,435,488...66,464,993
Ensembl chr16:66,434,251...66,464,952 		JBrowse link
G FBXW7 F-box and WD repeat domain containing 7 ISO ClinVar Annotator: match by term: Papillary renal cell carcinoma, sporadic ClinVar PMID:26619011 NCBI chr 7:98,894,261...99,105,955
Ensembl chr 7:98,892,504...99,106,084 		JBrowse link
G FGFR3 fibroblast growth factor receptor 3 ISO ClinVar Annotator: match by term: Papillary renal cell carcinoma, sporadic ClinVar PMID:8589699 PMID:8845844 PMID:9438390 PMID:9843049 PMID:10471491 More... NCBI chr27:46,958,444...46,974,032
Ensembl chr27:46,957,254...46,973,392 		JBrowse link
G HRAS HRas proto-oncogene, GTPase ISO ClinVar Annotator: match by term: Papillary renal cell carcinoma, sporadic
ClinVar Annotator: match by term: Papillary renal cell carcinoma, sporadic | ClinVar Annotator: match by term: Renal cell carcinoma, papillary, 1		 ClinVar PMID:11150980 PMID:16155195 PMID:16170316 PMID:16329078 PMID:16372351 More... NCBI chr 1:343,613...345,782
Ensembl chr 1:343,506...346,637 		JBrowse link
G LOC103231895 serine/threonine-protein kinase A-Raf ISO ClinVar Annotator: match by term: Papillary renal cell carcinoma, sporadic ClinVar PMID:24569458 PMID:26619011 NCBI chr  X:44,738,406...44,748,996
Ensembl chr  X:44,740,181...44,748,550 		JBrowse link
G LRRC56 leucine rich repeat containing 56 ISO ClinVar Annotator: match by term: Papillary renal cell carcinoma, sporadic ClinVar PMID:11150980 PMID:16155195 PMID:16170316 PMID:16329078 PMID:16372351 More... NCBI chr 1:352,131...370,276
Ensembl chr 1:355,982...369,633 		JBrowse link
G MET MET proto-oncogene, receptor tyrosine kinase ISO ClinVar Annotator: match by term: Papillary renal cell carcinoma, sporadic | ClinVar Annotator: match by term: Renal cell carcinoma, papillary, 1 ClinVar
OMIM		 PMID:1104268 PMID:9140397 PMID:9326629 PMID:9536098 PMID:9563489 More... NCBI chr21:85,370,574...85,486,405
Ensembl chr21:85,397,645...85,488,093 		JBrowse link
G MTOR mechanistic target of rapamycin kinase ISO ClinVar Annotator: match by term: Papillary renal cell carcinoma, sporadic ClinVar PMID:20190810 PMID:24631838 PMID:25741868 PMID:26018084 PMID:26619011 More... NCBI chr20:120,522,667...120,678,988
Ensembl chr20:120,525,737...120,679,020 		JBrowse link
G PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha ISO ClinVar Annotator: match by term: Papillary renal cell carcinoma, sporadic ClinVar PMID:15016963 PMID:15254419 PMID:15520168 PMID:15608678 PMID:15647370 More... NCBI chr15:10,218,034...10,304,874
Ensembl chr15:10,218,805...10,294,316 		JBrowse link
G PRCC proline rich mitotic checkpoint control factor ISO OMIM NCBI chr20:7,068,711...7,099,745
Ensembl chr20:7,068,333...7,099,339 		JBrowse link
G RHEB Ras homolog, mTORC1 binding ISO ClinVar Annotator: match by term: Papillary renal cell carcinoma, sporadic ClinVar PMID:26619011 NCBI chr21:119,652,692...119,704,833
Ensembl chr21:119,652,127...119,703,458 		JBrowse link
G TP53 tumor protein p53 ISO ClinVar Annotator: match by term: Papillary renal cell carcinoma, sporadic ClinVar PMID:1565143 PMID:7718482 PMID:7887414 PMID:8023157 PMID:8118819 More... NCBI chr16:7,047,686...7,065,567
Ensembl chr16:7,045,146...7,066,223 		JBrowse link
G VHL von Hippel-Lindau tumor suppressor ISO ClinVar Annotator: match by term: Papillary renal cell carcinoma, sporadic | ClinVar Annotator: match by term: Renal cell carcinoma, papillary, 1 ClinVar PMID:7660122 PMID:7728151 PMID:7784063 PMID:7987306 PMID:7987327 More... NCBI chr22:46,184,621...46,203,065
Ensembl chr22:46,184,756...46,204,428 		JBrowse link
G XIAP X-linked inhibitor of apoptosis exacerbates ISO mRNA:increased expression:kidney (human) RGD PMID:31964418 RGD:153344516
Renal Cell Carcinoma 1 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ASZ1 ankyrin repeat, SAM and basic leucine zipper domain containing 1 ISO ClinVar Annotator: match by term: Renal cell carcinoma 1 ClinVar PMID:28492532 NCBI chr21:86,042,400...86,108,247
Ensembl chr21:86,042,691...86,107,099 		JBrowse link
G ATM ATM serine/threonine kinase ISO ClinVar Annotator: match by term: Renal cell carcinoma 1 ClinVar PMID:10571946 NCBI chr 1:99,653,208...99,786,889
Ensembl chr 1:99,653,139...99,791,520 		JBrowse link
G CAPZA2 capping actin protein of muscle Z-line subunit alpha 2 ISO ClinVar Annotator: match by term: Renal cell carcinoma 1 ClinVar PMID:28492532 NCBI chr21:85,543,297...85,598,346
Ensembl chr21:85,543,271...85,601,370 		JBrowse link
G CFTR CF transmembrane conductance regulator ISO ClinVar Annotator: match by term: Renal cell carcinoma 1 ClinVar PMID:28492532 NCBI chr21:86,154,313...86,332,436 JBrowse link
G CTNNB1 catenin beta 1 ISO ClinVar Annotator: match by term: Renal cell carcinoma 1 ClinVar PMID:26822237 NCBI chr22:2,679,488...2,725,034
Ensembl chr22:2,684,022...2,723,949 		JBrowse link
G CUNH11orf65 chromosome unknown C11orf65 homolog ISO ClinVar Annotator: match by term: Renal cell carcinoma 1 ClinVar PMID:10571946 NCBI chr 1:99,804,191...99,879,834
Ensembl chr 1:99,804,218...99,827,182 		JBrowse link
G ELOC elongin C ISO ClinVar Annotator: match by term: Renal cell carcinoma 1 ClinVar PMID:26619011 NCBI chr 8:69,546,943...69,572,694
Ensembl chr 8:69,545,965...69,560,268 		JBrowse link
G MET MET proto-oncogene, receptor tyrosine kinase ISO ClinVar Annotator: match by term: Renal cell carcinoma 1 ClinVar PMID:1104268 PMID:9140397 PMID:9326629 PMID:9536098 PMID:9563489 More... NCBI chr21:85,370,574...85,486,405
Ensembl chr21:85,397,645...85,488,093 		JBrowse link
G MSH2 mutS homolog 2 ISO ClinVar Annotator: match by term: Renal cell carcinoma 1 ClinVar PMID:18325052 PMID:21926548 PMID:24506336 PMID:24763289 PMID:25637381 More... NCBI chr14:59,730,101...59,802,857
Ensembl chr14:59,729,789...59,802,819 		JBrowse link
G MTOR mechanistic target of rapamycin kinase ISO ClinVar Annotator: match by term: Renal cell carcinoma 1 ClinVar PMID:20190810 PMID:22729223 PMID:24631838 PMID:25599672 PMID:25741868 More... NCBI chr20:120,522,667...120,678,988
Ensembl chr20:120,525,737...120,679,020 		JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 ISO ClinVar Annotator: match by term: Renal cell carcinoma 1 ClinVar PMID:26619011 NCBI chr10:62,789,647...62,825,651
Ensembl chr10:62,790,124...62,825,339 		JBrowse link
G NRAS NRAS proto-oncogene, GTPase ISO ClinVar Annotator: match by term: Renal cell carcinoma 1 ClinVar PMID:1654209 PMID:2278970 PMID:2674680 PMID:3122217 PMID:6587382 More... NCBI chr20:18,953,273...18,966,002
Ensembl chr20:18,953,883...18,961,931 		JBrowse link
G PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha ISO ClinVar Annotator: match by term: Renal cell carcinoma 1 ClinVar PMID:15016963 PMID:15254419 PMID:15520168 PMID:15608678 PMID:15647370 More... NCBI chr15:10,218,034...10,304,874
Ensembl chr15:10,218,805...10,294,316 		JBrowse link
G PRCC proline rich mitotic checkpoint control factor ISO ClinVar Annotator: match by term: Renal cell carcinoma 1 ClinVar PMID:25741868 NCBI chr20:7,068,711...7,099,745
Ensembl chr20:7,068,333...7,099,339 		JBrowse link
G PTEN phosphatase and tensin homolog ISO ClinVar Annotator: match by term: Renal cell carcinoma 1 ClinVar PMID:1945792 PMID:9467011 PMID:9915974 PMID:10866302 PMID:11051241 More... NCBI chr 9:81,308,058...81,412,386
Ensembl chr 9:81,309,099...81,409,146 		JBrowse link
G RHEB Ras homolog, mTORC1 binding ISO ClinVar Annotator: match by term: Renal cell carcinoma 1 ClinVar PMID:26619011 NCBI chr21:119,652,692...119,704,833
Ensembl chr21:119,652,127...119,703,458 		JBrowse link
G SDHB succinate dehydrogenase complex iron sulfur subunit B ISO ClinVar Annotator: match by term: Renal cell carcinoma 1 ClinVar PMID:18728283 PMID:19576851 PMID:22835832 PMID:24055113 PMID:24092654 More... NCBI chr20:115,537,880...115,571,150
Ensembl chr20:115,538,026...115,571,142 		JBrowse link
G SF3B1 splicing factor 3b subunit 1 ISO ClinVar Annotator: match by term: Renal cell carcinoma 1 ClinVar PMID:26619011 NCBI chr10:82,901,908...82,952,094
Ensembl chr10:82,899,079...82,952,071 		JBrowse link
G SF3B2 splicing factor 3b subunit 2 ISO ClinVar Annotator: match by term: Renal cell carcinoma 1 ClinVar PMID:26619011 NCBI chr 1:8,189,636...8,207,024
Ensembl chr 1:8,189,446...8,207,020 		JBrowse link
G ST7 suppression of tumorigenicity 7 ISO ClinVar Annotator: match by term: Renal cell carcinoma 1 ClinVar PMID:28492532 NCBI chr21:85,632,652...85,908,772
Ensembl chr21:85,632,792...85,909,049 		JBrowse link
G TP53 tumor protein p53 ISO ClinVar Annotator: match by term: Renal cell carcinoma 1 ClinVar PMID:253702 PMID:960674 PMID:1349175 PMID:1565143 PMID:1565144 More... NCBI chr16:7,047,686...7,065,567
Ensembl chr16:7,045,146...7,066,223 		JBrowse link
G VHL von Hippel-Lindau tumor suppressor ISO ClinVar Annotator: match by term: Renal cell carcinoma 1 ClinVar PMID:7563486 PMID:7660122 PMID:7728151 PMID:7784063 PMID:7977367 More... NCBI chr22:46,184,621...46,203,065
Ensembl chr22:46,184,756...46,204,428 		JBrowse link
G WNT2 Wnt family member 2 ISO ClinVar Annotator: match by term: Renal cell carcinoma 1 ClinVar PMID:28492532 NCBI chr21:85,955,517...86,005,664
Ensembl chr21:85,955,145...86,001,730 		JBrowse link
Renal Cell Carcinoma, Xp11-Associated term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TFE3 transcription factor binding to IGHM enhancer 3 ISO ClinVar Annotator: match by term: Renal cell carcinoma, Xp11-associated OMIM
ClinVar		 NCBI chr  X:46,141,377...46,155,445
Ensembl chr  X:46,140,543...46,155,372 		JBrowse link
Sporadic Papillary Renal Cell Carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BRAF B-Raf proto-oncogene, serine/threonine kinase ISO ClinVar Annotator: match by term: Papillary renal cell carcinoma, sporadic ClinVar PMID:12068308 PMID:12198537 PMID:12447372 PMID:12460918 PMID:12460919 More... NCBI chr21:109,495,525...109,690,261 JBrowse link
G ERBB2 erb-b2 receptor tyrosine kinase 2 ISO ClinVar Annotator: match by term: Papillary renal cell carcinoma, sporadic ClinVar PMID:18413839 PMID:22046346 PMID:23220880 PMID:25157968 PMID:26619011 NCBI chr16:66,435,488...66,464,993
Ensembl chr16:66,434,251...66,464,952 		JBrowse link
G FBXW7 F-box and WD repeat domain containing 7 ISO ClinVar Annotator: match by term: Papillary renal cell carcinoma, sporadic ClinVar PMID:26619011 NCBI chr 7:98,894,261...99,105,955
Ensembl chr 7:98,892,504...99,106,084 		JBrowse link
G FGFR3 fibroblast growth factor receptor 3 ISO ClinVar Annotator: match by term: Papillary renal cell carcinoma, sporadic ClinVar PMID:8589699 PMID:8845844 PMID:9438390 PMID:9843049 PMID:10471491 More... NCBI chr27:46,958,444...46,974,032
Ensembl chr27:46,957,254...46,973,392 		JBrowse link
G HRAS HRas proto-oncogene, GTPase ISO ClinVar Annotator: match by term: Papillary renal cell carcinoma, sporadic ClinVar PMID:11150980 PMID:16155195 PMID:16170316 PMID:16329078 PMID:16372351 More... NCBI chr 1:343,613...345,782
Ensembl chr 1:343,506...346,637 		JBrowse link
G LOC103231895 serine/threonine-protein kinase A-Raf ISO ClinVar Annotator: match by term: Papillary renal cell carcinoma, sporadic ClinVar PMID:24569458 PMID:26619011 NCBI chr  X:44,738,406...44,748,996
Ensembl chr  X:44,740,181...44,748,550 		JBrowse link
G LRRC56 leucine rich repeat containing 56 ISO ClinVar Annotator: match by term: Papillary renal cell carcinoma, sporadic ClinVar PMID:11150980 PMID:16155195 PMID:16170316 PMID:16329078 PMID:16372351 More... NCBI chr 1:352,131...370,276
Ensembl chr 1:355,982...369,633 		JBrowse link
G MTOR mechanistic target of rapamycin kinase ISO ClinVar Annotator: match by term: Papillary renal cell carcinoma, sporadic ClinVar PMID:20190810 PMID:24631838 PMID:25741868 PMID:26018084 PMID:26619011 More... NCBI chr20:120,522,667...120,678,988
Ensembl chr20:120,525,737...120,679,020 		JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor severity ISO protein:increased expression:kidney (human)
mRNA:increased expression:renal cortex (human)		 RGD PMID:17409424 PMID:19384955 RGD:7240562 RGD:7240563 NCBI chr 8:122,282,989...122,288,392
Ensembl chr 8:122,282,630...122,288,384 		JBrowse link
G PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha ISO ClinVar Annotator: match by term: Papillary renal cell carcinoma, sporadic ClinVar PMID:15016963 PMID:15254419 PMID:15520168 PMID:15608678 PMID:15647370 More... NCBI chr15:10,218,034...10,304,874
Ensembl chr15:10,218,805...10,294,316 		JBrowse link
G RHEB Ras homolog, mTORC1 binding ISO ClinVar Annotator: match by term: Papillary renal cell carcinoma, sporadic ClinVar PMID:26619011 NCBI chr21:119,652,692...119,704,833
Ensembl chr21:119,652,127...119,703,458 		JBrowse link
G TP53 tumor protein p53 ISO ClinVar Annotator: match by term: Papillary renal cell carcinoma, sporadic ClinVar PMID:1565143 PMID:7718482 PMID:7887414 PMID:8023157 PMID:8118819 More... NCBI chr16:7,047,686...7,065,567
Ensembl chr16:7,045,146...7,066,223 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 15272
    disease of cellular proliferation 7115
      cancer 5154
        cell type cancer 3540
          carcinoma 2990
            adenocarcinoma 1559
              renal cell carcinoma 339
                Papillary Thyroid Carcinoma, with Papillary Renal Neoplasia 0
                Renal Cell Carcinoma 1 23
                Renal Cell Carcinoma, Xp11-Associated 1
                SMARCB1-deficient renal medullary carcinoma 0
                childhood kidney cell carcinoma 0
                chromophobe renal cell carcinoma + 3
                clear cell renal cell carcinoma 51
                collecting duct carcinoma 0
                cystic renal cell carcinoma 0
                hereditary renal cell carcinoma + 11
                mucinous tubular and spindle renal cell carcinoma 0
                multilocular clear cell renal cell carcinoma 0
                papillary renal cell carcinoma + 18
                renal cell carcinoma with MiT translocations + 0
                sarcomatoid renal cell carcinoma 0
Path 2
Term Annotations click to browse term
  disease 15272
    disease of cellular proliferation 7115
      Neoplasms by Site 6590
        Urogenital Neoplasms 2084
          Urologic Neoplasms 678
            urinary system cancer 627
              kidney cancer 450
                renal carcinoma 345
                  renal cell carcinoma 339
                    Papillary Thyroid Carcinoma, with Papillary Renal Neoplasia 0
                    Renal Cell Carcinoma 1 23
                    Renal Cell Carcinoma, Xp11-Associated 1
                    SMARCB1-deficient renal medullary carcinoma 0
                    childhood kidney cell carcinoma 0
                    chromophobe renal cell carcinoma + 3
                    clear cell renal cell carcinoma 51
                    collecting duct carcinoma 0
                    cystic renal cell carcinoma 0
                    hereditary renal cell carcinoma + 11
                    mucinous tubular and spindle renal cell carcinoma 0
                    multilocular clear cell renal cell carcinoma 0
                    papillary renal cell carcinoma + 18
                    renal cell carcinoma with MiT translocations + 0
                    sarcomatoid renal cell carcinoma 0
paths to the root